Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"KRAB-ZNF"”.
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Deep vertebrate roots for mammalian krab zinc-finger transcription factors
KRAB-associated C2H2 zinc-finger (KRAB-ZNF) proteins are the products of a rapidly evolving gene family that traces back to early tetrapods, but which has expanded dramatically to generate an unprecedented level of species-specific diversity. While most attention has been focused on the more …
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Comparison of orthologs across multiple species by various strategies
… yet. For example, the vertebrate roots of the KRAB-ZNF family in particular and of polydactyl ZNF genes in general, remain somewhat mysterious. In addition, due to its repeating gene structure and the fact that they often reside as clusters, these genes can be difficult to model correctly with …
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Gene duplication and alternative splicing play a role in modulating the functions of the ZNF286A transcription factor
… a novel zinc finger transcription factor (TF), ZNF286A, which is conserved in all eutherians and marsupials and provide evidence that this novel TF plays a role in regulation of mammalian neurogenesis. ZNF286 occurs as a unique gene in most species. However, we demonstrate evidence that a gene …
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THE ROLE OF ROMA IN MOUSE MAMMARY EPITHELIAL CELLS
Epithelial to Mesenchymal Transition (EMT) and its reversal, via Mesenchymal to Epithelial Transition (MET), describes the highly coordinated cycle of epithelial plasticity by which normal tissues are remodelled and repositioned during development. Previous studies have characterised the role of …