Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"KPNA2"”.
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Vaccinia virus BTB-Kelch proteins
… Specifically, A55 associates with importin KPNA2 and impairs the interaction between KPNA2 and p65, hence reducing p65 importation into the nucleus. A55 interacts with Cul3 directly and with high affinity, although the ability to inhibit NF-κB is independent of binding Cul3. In contrast, C2 …
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Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)
… regulates the interaction of RNMT with KPNA2 (Importin-a), which was found to inhibit RNMT activity in vitro. RNMT T77 phosphorylation is required for normal cell proliferation suggesting an important biological function. Initial experiments indicated that RNMT T77 phosphorylation …
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Investigating the role of nuclear transport proteins secreted by cancer cells
… adaptor protein, Karyopherin subunit alpha 2 (Kpna2). IP-MS of Kpnb1's binding partners secreted from cancerous and non-cancerous cells, although having a relatively low yield, identified Histones, an Actin protein (Actin cytoplasmic 1, N-terminally processed (ACTB)) and Laminin b. These …