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Showing 1 to 4 of 4 for “"KN-93"”.
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Die Rolle der Kalzium-Calmodulin-abhängigen-Proteinkinase II δc (CaMKIIδc) bei der Radikal-vermittelten Zytotoxizität in isolierten ventrikulären Kaninchenmyozyten
… Test der Gegenhypothese wurden die Inhibitoren KN-93 und Ranolazin eingesetzt. Schließlich konnte gezeigt werden, dass Sauerstoffradikale über eine Ca2+-abhängige Aktivierung der CaMKIIδc eine Verstärkung des späten Na+ - Stroms verursachen, was wiederum eine Na+ - und Ca2+ - Überladung der …
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The role of ionotropic glutamate receptors in chronic central pain after spinal cord injury
… CaMKII. Application of CaMKII inhibitor, KN-93, during recording 35 days post injury, reduces spinal hyperexcitability induced by SCI. \r\n
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Mode of action of FMRFamide-like peptide on drosophila body wall muscle conractions
… respectively. Furthermore, a CaMKII inhibitor, KN-93, did not affect the ability of peptide to increase muscle tonus. Thus, al though DPKQDFMRFamide acts through a G-protein coupled FMRFamide receptor, it does not appear to act via cAMP, cGMP, IP3, PLC or CaMKl1. The mechanism through which the …
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Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells
… kinase II (CaMK-II) inhibitor (KN-93) abolished PGF potentiation of Butaprost-mediated cAMP release. Using short interfering RNA (siRNA) molecules targeted against the adenylyl cyclase 3 (AC3) isoform, the study showed the isoform to be responsible for the cross-talk between the …