Global ETD Search
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Showing 1 to 6 of 6 for “"KLRG1"”.
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Phänotyp und Funktion KLRG1-exprimierender Lymphozyten der Maus
… "Killer cell Lectin-like receptor G1" (KLRG1) ist ein Typ-II-Transmembranprotein, dessen Expression auf Subpopulationen von T-Lymphozyten und Natürlichen Killerzellen beschränkt ist. Die vorliegende Arbeit hatte zum Ziel, die differentielle Expression und mögliche Funktion von KLRG1 auf …
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T-Lymphozyten aus Nabelschnurblut tragen den Killer cell Lektin-like Receptor G1 (KLRG1) : eine phänotypische und funktionelle Charakterisierung
… des "Killer cell Lectin-like Receptor G1" (KLRG1) konnte bei adulten Mäusen und Menschen eine einzigartige Subpopulation von T-Zellen beschrieben werden, die phänotypisch den Effektor- bzw. Gedächtniszellen zuzurechnen sind und ihre Teilungsfähigkeit verloren haben. Überraschenderweise fand …
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Investigating the T cell-specific role of Interleukin-4 receptor alpha (IL-4Rα) in tuberculosis (TB)
… amounts of terminally differentiated (CD44+KLRG1+ ) which have a poor proliferative capacity despite secreting large amounts of IFN-γ. KLRG1 expression is also associated with a reduced ability to migrate into the lung parenchyma, the site of disease. We also found that these (CD44+KLRG1+ ) …
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Maintenance and function of antigen-specific CD4 T cells within the lung during tuberculosis
… CXCR5. Furthermore we find that a majority of KLRG1+ IFN-γ producing CD4 T cells are located in the lung-associated vasculature and not in the lung parenchyma as previously thought. However, the PD-1+ population that shares features with follicular helper (Tfh) and memory T cells is principally …
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Hyporesponsive synovial fluid T cells in rheumatoid Arthritis
… described marker for replicative senescence KLRG1 and the effector/memory marker CD45RO revealed that the populations of T cells present in the SF from arthritis patients with anergic and normally proliferating T lymphocytes are similar in seize and composition.
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Memory Potential, Molecular Characterization, and Translational Applications of The Novel Theo/Tceo T Cell Phenotype
… receptor Killer Cell Lectin-like Receptor G1 (KLRG1) which we collectively term ThEO.</p> <p>Herein, we demonstrate that the ThEO phenotype constitutes a stable T cell polarity capable of recalling to subsequent antigen challenge. Despite expression of terminal differentiation markers, ThEO …