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Showing 1 to 1 of 1 for “"KIF18A"”.
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Whole genome doubling confers unique genetic vulnerabilities on tumor cells
… that the gene encoding for the mitotic kinesin KIF18A is dispensable for mitosis in diploid cells, but becomes critical for accurate chromosome segregation and viability in WGD+ cells, making it an attractive drug target. Collectively, this work revealed new strategies to specifically target …