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Showing 1 to 1 of 1 for “"KH domain, DDX43, DDX53, substrate specificity, EMSA, SELEX, ChIP-Seq, CLIP-Seq, NMR spectroscopy"”.
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Structure and Function of KH Domain in DDX43 and DDX53 Cancer Antigen Helicases
DDX43 and DDX53 are two cancer/testis antigens that are overexpressed in various tumors, but absent or expressed at very low levels in normal tissues; therefore, both are proposed to be valid candidates for therapeutic targets. DDX43 and DDX53 belong to the DEAD-box RNA helicase family, and contain …