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Showing 1 to 20 of 78 for “"KH"”.
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Measurements of the spontaneous polarization in KH(2)PO(2)
Measurements of the spontaneous polarization of KH(2)PO(4) within 1 K if the ferroelectric transition are reported. the measurement employed the electrocaloric effect, allowing simultaneous determination of the polarization and its temperature derivative. The derivative computed from polarization …
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Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation
… profiles of mice lacking Nova-1 or FMRP. The KH2 and RGG box RNA-binding domains of FMRP bind specific RNA motifs that form kissing complex and G-quartet structures, respectively. We find that the association of FMRP with polyribosomes in both mouse brain and human neuroblastoma cells is …
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Structure and Function of KH Domain in DDX43 and DDX53 Cancer Antigen Helicases
… RNA helicase family, and contain a K-homology (KH) domain in their N-terminal regions and a helicase core domain in their C-terminal regions. The KH domain was first characterized in the human heterogeneous nuclear ribonucleoprotein K (hnRNP K). The typical function of KH domain is to bind …
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Functional Analysis of the 15 KH Domain Human Nucleic Acid Binding Protein, Vigilin
… 15 related, but nonidentical K homology (KH) nucleic acid binding domains. Despite its high level of conservation among species, the precise function(s) of vigilin remain unclear. Vigilin was identified in our lab as the trans-acting factor which binds to the 3' untranslated region of …
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Knowing How: An Empirical, Functionalist Approach
… to divide around the question: is knowledge how (KH) reducible to, or a kind of, knowledge that (KT), or are they fundamentally distinct categories of knowledge? I argue for the latter view, and I base my argument in the claim that KH and KT serve fundamentally different functional roles - …
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Internal pressure's role in the selectivity of the bromine radical
… (kC) vs hydrogen abstraction from toluene (kH) by bromine atom was found to vary by nearly a factor of twenty as a function of solvent. The observed rate constant ratios correlate with the cohesive energy density of the solvent, which is approximately equal to the internal pressure (kC/kH is …
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Investigating Novel Inhibitors of Epithelial - Mesenchymal Transition (EMT) and Cancer Stem Cells (CSCs) in Pancreatic Cancer
… developed a small molecule inhibitor of HuR, KH-3, and evaluated the activities of KH-3 on pancreatic cancer EMT and CSCs. Our data showed that KH-3 directly bound to HuR and interfered the binding of HuR with its target mRNAs. As an HuR/mRNA disruptor, KH-3 treatment successfully mimicked the …
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Nonlinear effects on interfacial wave growth into slug flow
… the focus of this study. The Kelvin-Helmholtz (KH) instability is the traditional model for predicting interfacial instability in stratified flows. This linear instability occurs when the lower phase inertia and the pressure from the upper phase overcome the stabilizing effects of gravity and …
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Algorithms for three-dimensional free-form object matching
… and no scaling effects, namely the KH and the umbilic method. The KH method establishes a correspondence between two objects by utilizing the Gaussian and mean curvatures. The umbilic method uses the qualitative properties of umbilical points to find correspondence information …
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Characterization of Heat Transfer Enhancement for an Oscillating Flat Plate-Fin
… as a single parameter “plunge velocity” (0.25 ≤ kh ≤ 4) instead of the individual frequency and amplitude values. For kh > 0.5 a significant increase in Nusselt number ( is observed compared to a stationary plate. With increasing kh or more vigorous oscillations, the increase in becomes more …
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Multifluid Kelvin-Helmholtz instability in weakly ionised astrophysical plasmas
… in particular the Kelvin-Helmholtz (KH) instability. The KH instability could, for example, play a role in the momentum transfer between the bowshock of a protostellar jet and its surrounding molecular cloud. In particular, changes to the development of the KH instability as a result …
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The Paraneoplastic Antigen Nova-1 is a Neuron Specific and Sequence Specific RNA Binding Protein
… symptoms seen in POMA. Nova-1 contains three KH type RNA binding motifs, and binds RNA in vitro via these KH motifs. Mutations within the core of the KH motif abolish specific RNA binding. Utilizing RNA selection, we have identified an in vitro RNA ligand for Nova-1 consisting of three UCAUY …
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Towards Understanding Helicase and Chaperone Activities in the RNA Degradosome
… and its relationship to the RNA binding KH domains. Utilizing a point mutation in the DEAD box of RhlB, I have found increased RNA affinity to mutant RhlB, the potential structure of Hfq — an RNA chaperone — bound to the sRNA ChiX, and a structural correlation between the RNase E small …
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The Effect of Posture During CPR on Rescuer Muscular Fatigue Development and CPR Quality
… of CPR, on a training manikin, at four heights (KH, LH, FH, WH). EMG of sixteen muscles, kinematics of the manikin, and kinetic data at the hands were collected. The MPF identified that four, six, four, and nine muscles fatigued during KH, LH, FH, and WH, respectively. Furthermore, there was a …
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Diffusion In Strong And Weak Mixed Electrolyte Solutions
… for three compositions of the system KCl + KH{dollar}sb2{dollar}PO{dollar}sb4{dollar} + H{dollar}sb3{dollar}PO{dollar}sb4{dollar} + H{dollar}sb2{dollar}O at 25{dollar}spcirc{dollar}C. It is shown that pH gradients in KH{dollar}sb2{dollar}PO{dollar}sb4{dollar} + …
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Physical and chemical properties of artificial soil with humified and non-humified organic matters
… (KC) and kaolin mixed with LM Bio Humus Juice (KH). Physical and chemical properties such as Atterberg limit, moisture content, specific gravity and acidity level were determined to establish the basic characteristics of soil. Mineralogy and molecular characteristic of samples were determined …
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Structural and Functional Studies of ASCC1 in DNA and RNA Alkylation Damage Response
… ancient domains: nucleotide-binding K-Homology (KH) (associated with splicing, transcriptional regulation, and translational control) and two-histidine phosphodiesterase (PDE) (associated with hydrolysis of cyclic nucleotide phosphate bonds). Germline mutations link ASCC1 loss of function to …
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Analisi prestazionale del comportamento sismico di opere di sostegno in terra rinforzata
… trovata l'espressione del coefficiente critico kh,crit e del coefficiente sismico equivalente keq. Si è inoltre valutato il coefficiente di forma Cw, che entra in gioco nella stima degli spostamenti permanenti con il metodo di integrazione proposto da Newmark (1965). Per determinare gli …
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Kinetics of the ligand exchange reactions between bidentate ligands and rriethylenetetramine nickelate (II) and synthesis of boron (III) subphthalocyanines with various boron substitutions
… <p>k dt d[Ni(trien)] = ( − MP Ni(trien)(5MP) + kH, 5MP Ni(trien)(5MP) [H+]) [Ni(trien)][5mp]</p> <p>where: 5MP is 5-methyl-1,10-phenanthroline and k is the first order rate constant that has units of 1/time.</p> <p>kH, 5mp Ni(trien)(5mp) = 9.78 X 104 M-2 s-1</p> <p>and k5mp Ni(trien)(5mp) = 9.42 …
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