Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"K5"”.
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Preventing Thymus Involution In K5.Cyclin D1 Transgenic Mice Sustains The Naïve T Cell Compartment With Age
… a keratin 5 promoter-driven Cyclin D1 (K5.D1) transgene in thymic epithelial cells (TECs). Thymopoiesis occurs normally in K5.D1 transgenic thymi and sustains T cell output to prevent the age-associated decline of naïve T cells in the periphery. We find that K5.D1 recent thymic emigrants …
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Analysis of the genome organization and fitness traits of non-pathogenic Escherichia coli strain Nissle 1917 (O6:K5:H1)
… Escherichia coli strain Nissle 1917 (O6:K5:H31) and to compare these data with publicly available data on the genomes of different pathogenic and non-pathogenic E. coli strains and other closely related species. A cosmid genomic library of strain Nissle 1917 was screened for clones …
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Effects of Thymus Size and Involution On The Contribution of Recent Thymic Emigrants to The Peripheral T Cell Pool
… TCR diversity.</p> <p>Mice that express a K5.CyclinD1 transgene expression have a severely hyperplastic thymus that fails to undergo involution. Both thymocyte and TEC development appear normal in these mice. We have used the K5.CyclinD1 transgenic model to test the hypothesis that …
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Modulation of The Receptor Gating Mechanism and Allosteric Communication In Ionotropic Glutamate Receptors
… in heteromeric kainate receptor GluK2/K5 and NMDA receptor GluN1/N2A. Some of the major finding in this dissertation includes subunit arrangement of GluK2/K5 and its dynamics involved in resting and desensitized conditions. For the first time we have identified the conformational …
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Role of Stat3 In Keratinocyte Stem Cells During Skin Tumorigenesis
… the role of KSCs in skin tumorigenesis, K5.Stat3C transgenic (Tg) mice which express a constitutively active/dimerized form of Stat3 called Stat3C via the bovine keratin 5 (K5) promoter were studied. The number of CD34 and α6 integrin positive cells was significantly reduced in Tg mice as …
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Adaptive Laboratory Evolution of Scenedesmus obliquus for Increased Carbohydrate Content and Biomass Productivity
… with the goal of increased carbohydrate content: K5 and K7. Both were mutagenized for 5 seconds and cultivated in 50-mL Klavins reactors. K5 was maintained at 95 μmol/m<sup>2</sup>-sec for 16 hours/day, and K7 was maintained at 250 μmol/m<sup>2</sup>-sec for 6 hours/day. When evaluating the two …
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Determination of Thymic Epithelial Cell Composition and Proliferation During The Perinatal to Adult Transition
… and medullary TEC (mTEC) are expanded in the K5.D1 thymus, FACs analysis revealed a marked increase in a novel UEA-1<sup>int</sup> Sca-1- TEC subset, which is not readily classified as belonging to either the cTEC or mTEC lineage. In addition, low level expression of MHC class II and …
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The capsular polysaccharide of Actinobacillus pleuropneumoniae serotype 5A: role in serum resistance and characterization of the genetic basis for expression
… and to a lesser extent Escherichia coli K1 and K5 (kpsED, kpsMT). The J45 cpxDCBA gene cluster was able to partially complement kpsM::TnphoA or kpsT::TnphoA mutations within a plasmid-encoded E. coli K5 kps locus and restored sensitivity to a K5-specific bacteriophage, indicating that cpxDCBA …
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PLANAR GRAPHS, BIPLANAR GRAPHS AND GRAPH THICKNESS
… bipartite graphs that are not planar are K5 and K{3,3}. A biplanar graph is a graph whose edges can be colored using red and blue such that the red edges induce a planar subgraph and the blue edges induce a planar subgraph. In this thesis, we determine the smallest complete and complete …
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The role of credit unions in socio-economic development of Zambia
… OCX)) members and nearly five million Kwacha (K5, 000,000) worth of shares amongst themselves. Data was collected largely but not exclusively through questionnaire interviews, Data was analyzed by the use of various techniques such as percentages, frequency table and significance tests, It is …
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Gain-of-Function Mouse Models to Investigate Biological Roles of Prmt6
… expressing a Cre recombinase under a Keratin 5 (K5) promoter, as well as with a MMTV-Cre mouse line. I have conducted carcinogenesis studies with these mice. The K5-Cre crossed mice have been subjected to skin carcinogenesis study using the DMBA/TPA system and to a p53+/- genetic cross. The …
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Using S. pombe to Study the Biological Roles of the Histone Deacetylases Sir2 and Clr3 and the DEAD-Box RNA Helicase Ded1
… HDAC Clr3 in addition to H3K14, specifically H2B K5, 6, 10, and 15. Using fission yeast, this study also examined the biological consequence of medulloblastoma associated mutations of the DEAD-box ATP-dependent RNA helicase DDX3X. In fission yeast, Ded1 is an essential protein with connections to …
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Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments
… high levels of basal layer marker, keratin 5 (K5), and low levels of the early differentiation marker, K10, suggesting that the isolated keratinocytes have stem cell properties. When co-cultured with neonatal mouse mesenchymal cells using Transwells, the mesenchymal cells were able to elicit …
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The palaeobiology of the late Permian dicynodont Endothiodon (Therapsida, Anomodontia)
… from the Karoo Basin ofSouth Africa and from the K5 Formation of Mozambique, to date no studies of the functional morphology of the postcranial skeleton have been conducted. Three-dimensional models of forelimb and hindlimb elements were used in digital articulation, showing that mobility in the …
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Βιοδιεργασίες στην παραγωγή προβιοτικών γαλακτοκομικών προϊόντων με ακινητοποιημένα γαλακτικά βακτήρια σε πριβιοτικούς φορείς
… προβιοτικού γαλακτικού βακτηρίου (L. paracasei K5) και ακολούθησε η ακινητοποίηση του σε απολιγνινοποιημένο φλοιό σιταριού και η χρήση του στην παραγωγή λευκού τυριού άλμης. Τα γαλακτοκομικά προϊόντα που παρήχθησαν μελετήθηκαν ως προς τα αρωματικά, φυσικοχημικά και οργανοληπτικά χαρακτηριστικά …
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MuSciQ- A Musical Curriculum for Math
Music and math are related in that 1) they both rely on the basic understanding of numbers, proportions, intervals, measurements, and operations and 2) both require levels of abstract thinking and symbolic notation. Studies link music and math by examining, for example, how music may play a role in …
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Entwicklung von Silizium-Mikrostreifen-Detektormodulen für den ATLAS Semiconductor Tracker
… <br>Das Rauschverhalten von Detektormodulen mit K5-Hybriden wurde mit Hilfe des Kalibrierungsschaltkreises des ABCD3TA untersucht. Die Verstärkung der Ausleskanäle beträgt etwa 50mV/fC. Wie erwartet nimmt das Rauschen mit der Streifenkapazität zu. Ein inneres Modul hat eine ENC von 1020±30 …
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Special TK5 in graphs containing K4-
… that every nonplanar 5-connected graph contains TK5 . Ma and Yu proved the conjecture for graphs containing K4-. In this dissertation, we strengthen their result in two ways. The results will be useful for completely resolving the Kelmans-Seymour conjecture. Let G be a 5-connected nonplanar graph …
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Exploring the factors at play to make wastewater biorefineries a reality
… al., 2014) and Water Research Commission (WRC) K5/2380 project titled “Towards Wastewater Biorefineries: integrated bioreactor and process design for combined water treatment and resource productivity” (Harrison, et al., 2017). While the project focused on a global and national review on …
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