Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 59 for “"K. pneumoniae"”.
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Redefining gene distributions in K. pneumoniae and E. coli using large public datasets
… distributions in Escherichia coli and Klebsiella pneumoniae. While both K. pneumoniae and E. coli are found in the guts of healthy individuals, as well as in animals and in the environment, they are particularly relevant organisms to study, as they represent key players in the dissemination of …
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Identification of new therapeutic compounds against carbapenemase-producing Klebsiella pneumoniae using a novel agar-based high-throughput microarray compound screening approach
Klebsiella pneumoniae, a Gram-negative bacterium, is a common cause of hospital-acquired pneumonia, urinary tract infections (UTIs), bacteraemia, septicaemia, and wound/surgical site infections. Over the years, the pathogen developed resistance to most β-lactam antibacterial drugs used in clinical …
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Exploring the Polyclonal Antibody Responses Induced by Klebsiella pneumoniae Derived Outer-Membrane Vesicles
… faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. Of these, Klebsiella pneumoniae stands out due to its vast genomic diversity with only a small percentage of the genome being dedicated to the core genes, while the …
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Conservation Of The Intracellular Bacterial Community Pathogenic Pathway In Urinary Tract Infection
… several other uropathogens, including Klebsiella pneumoniae, are also significant causative agents. In a murine cystitis model, UPEC utilize a multistep pathogenic pathway in which they invade and form intracellular bacterial communities: IBCs) within bladder facet cells. Type 1 pili, adhesive …
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Identification and characterisation of cephalosporins and carbapenem-resistant Klebsiella pneumoniae isolates from Misrata, Libya
… of ESBL and carbapenemase-producing K. pneumoniae isolates from Misrata. Materials and Methods: Two hundred Gram-negative bacillus isolates were collected and identified from hospitals and pathology laboratories in Misrata. Following antimicrobial susceptibility screening, those showing …
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The role of lipid A in the virulence of ESKAPE pathogens
… Acinetobacter<br/>baumannii and Klebsiella pneumoniae have been highlighted as critical priority<br/>pathogens for research and development of novel therapeutics. Both of these<br/>pathogens share notoriety for their readiness to develop resistance to all antibiotics currently in …
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Epidemiological Typing and Mechanisms of Antibiotic Resistance in Clinically Relevant Klebsiella Pneumoniae Isolated at St. Marina University Hospital – Varna // Епидемиологично типизиране и механизми на антибиотична резистентност в клинично значими Klebsiella pneumoniae, изолирани в УМБАЛ „Света Марина“, Варна
… проучваната колекция от 1084 изолата Klebsiella pneumoniae. Резистентните на цефалоспорини трета генерация изолати демострираха във висока степен резистентност към представители и на други антибиотични групи – piperacillin/tazobactam(96.5%),ciprofloxacin (96.5%), trimethoprime/sulphometoxazole …
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Structural analysis of capsular polysaccharides produced by some emerging Klebsiella pneumoniae serotypes
Klebsiella pneumoniae (K. pneumoniae), a Gram-negative pathogenic bacterium, is a leading cause of neonatal sepsis in low- and middle-income countries (LMICs). Due to rapidly increasing anti-microbial resistance (AMR), it has been ranked among the “critical-priority 1” pathogens to human health by …
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The Effect of O Antigen Loss on the Protein Composition and Inflammatory Response Elicited by Klebsiella pneumoniae
Klebsiella pneumoniae is a Gram-negative pathogen associated with numerous infections. Like all Gram-negative bacteria, K. pneumoniae naturally release outer membrane vesicles (OMVs) during all stages of cellular growth. OMVs are composed of the outer membrane components such as lipopolysaccharide …
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Molecular detection, quantification and characterization of extended-spectrum β-lactamase (ESBL)- and AmpC-encoding genes in a cucumber agroecosystem
… bacteria such as Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa are antibiotic resistant (AR) and found on fresh produce that is consumed raw, difficult-to-treat infections may result later. In addition, this may lead to ARB remaining in the consumer’s gut. This may …
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Pesquisa de genes de resistência a aminogliosídios em isolados de colonização e infecção de Klebsiella pneumoniae e enterobacter aerogenes portadores do gene blaKPC provinentes de hospitais de Recife-PE
Klebsiella pneumoniae e Enterobacter aerogenes têm se destacado como importantes agentes de infecções relacionadas à assistência à saúde (IRAS), causando principalmente infecções de feridas, dos tratos urinário e respiratório, além de sepse. Essas infecções são causadas por linhagens bacterianas …
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Antibacterial and Laundering Properties of Ams and Phmb as Finishing Agents for Healthcare Workers Uniforms
… Staphylococcus aureus (S. aureus) and Klebsiella pneumoniae (K. pneumoniae) bacteria, (b) fabric weight, (c) fabric thickness, and (d) breaking strength loss due to abrasion. Multiple Analysis of Variance (MANOVA) and Two-way Analysis of Variance (ANOVA) were used to examine the effects of the …
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The microbiology of diabetic foot infections: a Ghanaian perspective
… 2 multidrug resistant DFU isolates, Klebsiella pneumoniae and Proteus mirabilis in maintaining the chronicity of diabetic foot ulcers. Using 3 in vitro biofilm models; the conventional microtitre plate and Minimum Biofilm Eradication Concentration (MBEC™) High-Throughput assays and the …
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Predictors of Carbapenem Resistant Gram-negative Bacteria in a Consortium of Academic Medical Center Hospitals
… the carbapenems are carbapenemase-producing K. pneumoniae Purpose: To determine if there is an association between the volume and composition of antibiotic use, geography, severity of illness and rates of carbapenem-resistant P. aeruginosa and K. pneumoniae. Methods: This is a retrospective …
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Regulation of nitrogen fixation in Klebsiella pneumoniae: NifL, one protein transducing two environmental signals to the nif-transcriptional activator NifA
… der NifA abhängigen Expression von K. pneumoniae ø(nifH-lacZ)-Fusionen in verschiedenen genetischen Hintergründen haben wir die Sauerstoffregulation der NifL Aktivität in E. coli and K. pneumoniae Stämmen untersucht. In Stämmen beider Organismen mit fnr-Deletionen konnte die Inhibierung …
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Investigations of Carbapenem-resistant Klebsiella species and associated clinical considerations
… tests identified the strains as Klebsiella pneumoniae (n = 36) and Klebsiella oxytoca (n = 3). Detailed whole-genome sequence (WGS) analyses showed the K.oxytoca were Klebsiella michiganensis and one of the K. pneumoniae strains to be Klebsiella variicola subsp. variicola. The K. …
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Applying at scale genomic and phenotypic approaches to study pathogens linked to nosocomial transmission and disease
… threats: the Gram-negative bacterium Klebsiella pneumoniae, the seasonal respiratory virus influenza and the pandemic coronavirus SARS-CoV-2. Using isolates prospectively collected at Cambridge University Hospitals, I have utilised a combination of genomic, epidemiological and clinical datasets …
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Bacteriemias por Escherichia coli productor de beta-lactamasas de espectro extendido epidemiología clínica y molecular
… los microorganismos productores de BLEE, K. pneumoniae ha sido el más estudiado desde el punto de vista epidemiológico y clínico, y del que se conocen más aspectos de su comportamiento. Asimismo, son abundantes ya los estudios microbiológicos acerca de E. coli productor de BLEE, pero existe …
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The yield of nasopharyngeal bacteria from culture compared to polymerase chain reaction in South African children with lower respiratory tract infection
… (IQR 3.8; 18.9) months; 0.2% HIV-infected]. S. pneumoniae, S. aureus, M. catarrhalis, H. influenzae and K. pneumoniae were the predominant bacteria detected by either method. Concordance between culture and PCR for S. pneumoniae, S. aureus, and K. pneumoniae was 84.9%, 89.7% and 86.3% …
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EXTENDED-SPECTRUM Β-LACTAMASE-, AMPC- AND CARBAPENEMASE-PRODUCING BACTERIA IN DOGS AND CATS
… AmpC e carbapenemasi in E. coli e Klebsiella pneumoniae. Quest’ultimo è un patogeno clinicamente significativo spesso associato a resistenza agli antimicrobici di massima priorità e ad altri meccanismi di resistenza come la produzione di biofilm nei batteri isolati da campioni urinari. La …
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