Global ETD Search
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Showing 1 to 4 of 4 for “"K-(ATP) channel"”.
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K(ATP) channel Kir62 subunit distribution differs between muscles and between fiber types in skeletal muscle
The activity of the ATP-sensitive potassium (KATP) channel, whose sensitivity to ATP and ability to permit K+ flux together allow the channel to couple the metabolic state of a cell to its membrane excitability, is important in several tissues for the maintenance of glucose homeostasis and …
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Functional cell biology and molecular pharmacology of ATP sensitive potassium channels.
Adenosine triphosphate (ATP) sensitive potassium channels (K ATP) transduce changes in cellular metabolism into changes in membrane potential. Activation of K ATP channels causes vascular smooth muscle to hyperpolarize. This leads to a relaxation of the pre-contracted muscle. Inhibition of K ATP …
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The Neurotoxicity of Insecticides to Striatal Dopaminergic Pathway
… function in PD, and a high density of K⁺ATP channels are present in substantia nigra, which play an important role in the maintenance of the membrane potential under metabolic stress. Therefore, in the second objective, I investigated the effect of K⁺ATP channel blockage on the …
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Regulation of glucagon secretion from pancreatic alpha cells
… excitable and equipped with different ion channels. But unlike β-cells, α-cells electrical activity is only possible within a narrow window of low K(ATP) channel activity. At low glucose, the K(ATP) channels are almost fully – but not completely –inhibited. This allows firing of action …