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Showing 1 to 8 of 8 for “"Juglone"”.
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Dermatophyte Respiration Antagonism in Vitro by Juglone
Centuries before juglone was isolated and structurally analyzed it was employed as a medicinal ingredient in combating venereal diseases, eczema, mycotic infections, gastro-intestinal disorders and a number of varied pathologically unrelated diseases. Juglone, 5-hydroxy-1, 4-naphthoquinone, is a …
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In Vitro Investigation on Therapeutic Potential of Juglone, a Naphthoquinone from Walnuts against Pancreatic Cancer
Juglone, a naphthoquinone found in Juglandaceae family, which includes black walnut, European walnut, and butter nut possess various biological activities. The anti-cancer properties of juglone has been reported; however, the effect of juglone in pancreatic cancer (PC) has not been elucidated yet. …
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A Multifunctional Solution Composed Of TMPyP, 1,5-DHN, And Fe(III) Ions That Produces Reactive Oxygen Species (ROS) In Aerobic, Anaerobic, And H2O2 Environments
… in both environments, 1,5-DHN was oxidized to Juglone or derivatives of Juglone. Moreover, this multifunctional solution was found to generate ȮH and Juglone in a hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) rich environment without the presence of visible light. This multifunctional solution …
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Green Photochemistry: The synthesis of fine chemicals with sunlight
… to the research, namely the optimisation of juglone (5-hydroxy-1,4-naphthoquinone) synthesis under green conditions, the extension of the optimised procedure to a library of 1-naphthols and the investigation of photooxygenation reactions in alternative media. The dye-sensitised …
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Enhanced biohydrogen production and substrate utilization by co-culture fermentation with reduced extracellular electron shuttles
… as to utilize compounds including indigo dye, juglone, lawsone, fulvic acids and humic acids as alternative extracellular electron shuttles. The observed improvements in utilization of lignocellulosic hydrolysates and particularly utilization of xylose III support the feasibility of applying …
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Synthesis and evaluation of novel multi-target compounds for the treatment of Alzheimer's disease.
… against three cytotoxic stressors (A~2s-3s, juglone, and rotenone). Select compounds which had the strongest protective effects in cells were then tested for their in vitro activities against other targets of AD. Furthermore, the mechanism of their cell protective effects was investigated …
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Pin1 Inhibitors: Towards Understanding the Enzymatic Mechanism
… ketones, and 2) several natural products such as juglone, pepticinnamin E analogues, PiB and its derivatives obtained from a library screen. These Pin1 inhibitors show promise in the development of novel diagnostic and therapeutic anticancer drugs due to their ability to block cell cycle …
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Aspects of the chemistry of 1,4-naphthoquinones. An investigation of nucleophilic substitution reactions of alkylamines and hydroxyalyklamines on 1,4 napthoquinones and the role of solvent on the position of substitution.
Nucleophilic substitution reactions of alkylamines, cyclic alkylamines, and hydroxyalkylamines with 5-substituted-1,4-naphthoquinones have been studied. It has been found that the nature of the solvent employed in the reaction influences the position of mono-substitution at either the 2- or …