Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"JMJD6"”.
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The critical role of histone methylation in tumour progression and as anti-cancer targets in neuroblastoma
… been linked to gene transcriptional activation. JMJD6 is a bi-functional arginine demethylase and lysyl-hydroxylase. The JMJD6 gene is located on the chromosome 17q25 position. 17q21-gter gain has been identified as the most frequent chromosome alternation in neuroblastoma and an indicator of …
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The functional characterization of a novel protein, Liat1
… In addition to Ate1, Liat1 interacts with Jmjd6, a bifunctional enzyme with demethylase and lysl-hydroxylase activity. We show that Jmjd6 modifies Liat1 and prevents its nucleolar targeting through in a manner that requires its hydroxylation activity. In efforts to identify the Liat1 amino …
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Nucleosome repositioning in glioblastoma
… binding sites of CTCF, RBPJ, MYC, KLF9 and JMJD6, which I propose for the role of new liquid biopsy markers. Moreover, I studied differences in nucleosome occupancy at different classes of genomic features such as ALU repeats, which showed unexpected resemblance to transcription start sites. …