Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"JIP3"”.
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Understanding Neuronal Autophagic Lysosomal Pathways Through Genetic and Pharmacological Perturbations
… have complex morphology. The adaptor protein JIP3 is critical for this process. However, despite its importance to axonal lysosome retrograde transport, the role of JIP3 in axonal transport of less mature autolysosomes and autophagosomes in mammalian neurons has not yet been described. …
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CHARACTERIZATION OF THE ROLES OF MUSCLE-SYNTHESIZED BRAIN-DERIVED NEUROTROPHIC FACTOR AND PRESYNAPTIC TYROSINE RECEPTOR KINASE B IN MOTOR NEURON AXONAL TRANSPORT
… adaptor proteins, including dynactin and JIP3, which help bind cargo to motor proteins. Disruption of retrograde transport is a hallmark of several neuromuscular diseases, including SBMA, Huntington’s disease, and ALS. The roles of BDNF and TrkB are not well-characterized in muscle or …