Global ETD Search
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Showing 1 to 3 of 3 for “"JARID1"”.
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JMJC Domain-Containing Histone Demethylase 2 (Jhd2): Bridging the Gap between H3K4 Trimethylation and H3 Acetylation
… S. cerevisiae. Jhd2 is a homologue of the human JARID1 family of histone demethylases, which has four members: JARID1A, B, C and D. JARID1B is of particular interest because it has been shown to be up regulated in 90 percent of primary breast cancers. Furthermore, JARID1A has been shown to be up …
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JMJC Domain-Containing Histone Demethylase 2 (Jhd2): Bridging the Gap between H3K4 Trimethylation and H3 Acetylation
… S. cerevisiae. Jhd2 is a homologue of the human JARID1 family of histone demethylases, which has four members: JARID1A, B, C and D. JARID1B is of particular interest because it has been shown to be up regulated in 90 percent of primary breast cancers. Furthermore, JARID1A has been shown to be up …
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Molecular Functions of MLL PHD3 Binding to Its Ligands Cyp33 and H3K4Me3
… in H3K4Me3 and increase in recruitment of JARID1A and JARID1B, the H3K4 specific demethylases, at the MLL target gene promoters.</p> <p>To determine the transcriptional outcome of the MLL PHD3 binding to H3K4Me3 or Cyp33, we abrogated either H3K4Me3 binding or Cyp33 binding to the MLL PHD3 …