Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Ivermectin"”.
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Environmental Fate of Ivermectin and its biological metabolites in Soils: Potential implications for the Environmental Impact of Ivermectin Mass Drug Administration for Malaria Control
… livestock near humans with an insecticide like ivermectin (IVM) to kill zoophagic malaria vectors. However, ivermectin pharmacokinetics data suggests that most IVM-administered drugs remain intact, and more than 90 % of this drug is eliminated in feces. Biological metabolites: …
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The Effects of Treating Dauer C. Elegans with Natural Anthelmintics and Ivermectin
… grow, or move. Alliin, Wormwood extract, and Ivermectin were used to treat the worms. A motility assay was conducted before, during, and after the treatments. As a result, the wormwood extract was effective at killing both wild and odr-3 mutant strains in either dauer or non-dauer worms. The …
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The potential health impact of ivermectin mass drug administration for malaria control on swine in Mozambique
… of a larger clinical trial assessing the use of ivermectin (IVM) mass drug administration to humans and pigs for the control of malaria vectors in the Mopeia district in Mozambique, a longitudinal study to assess the impact of IVM administration on pig health was performed. METHODS: Beginning in …
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The Impact of Ivermectin Treatment in Cattle on Dung Degradation and Fauna Abundance and Diversity in Tanzania
Ivermectin also called the wonder drug has been used over the years to control internal and external parasites in livestock. In humans it has been used for the control of several neglected tropical diseases. With regards to efforts to control malaria, mass drug administration (MDA) of ivermectin in …
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Effects of Ivermectin on Lungworm Infection and Lamb Survival of Bighorn Sheep in Custer State Park, South Dakota
I examined the effects of the anthelmintic drug, ivermectin, on lungworm (Muellerius capillaris) densities, reproductive rates, and survival of lambs of free-ranging bighorn sheep in Custer State Park (CSP), South Dakota. Three distinct ewe herds in CSP allowed for comparisons among ewes given o, …
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Are Post-Transcriptional RNA Modification Events in the Glutamate-Gated and GABA-Gated Chloride Channels of Anopheles minimus and Anopheles dirus associated with Ivermectin Insensitivity?
… have highlighted the effective use of the drug ivermectin (IVM) as a malaria vector control tool, which kill mosquitoes by having a detrimental effect on neuronal functions by acting on the glutamate-gated (GluCl) and the GABA-gated (RDL) chloride channels. The mechanism by which this is …
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P-glycoprotein and membrane permeability as determinants of xenobiotic bioavailability and bioaccumulation
… relevant pharmaceuticals, tetracycline and ivermectin, and the carcinogen benzo[a]pyrene in catfish. The pesticide dieldrin and surfactant linear alkylbenzene sulfonate (LAS) were selected as mixture components thought to have potential interactions with these determinants of disposition. …
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Isolierte Gehirn-Kapillaren als in vitro-Modell der Blut-Hirn Schranke
… der Transport der beiden Arzneistoffe Ivermectin und Octreotid an der Blut-Hirn Schranke auf eine mögliche Beteiligung der Transporter-Proteine P-Glykoprotein und Mrp2 hin untersucht. Für das Anthelminthikum Ivermectin konnte aufgrund von Sekretions-Untersuchungen gezeigt werden, daß …
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Validação de método bioanalítico para avaliação da influência da ivermectina e ciclofosfomida na farmacocinética (pk) da carboplatina: ensaio pré-clínico
… with carboplatin preceded by application of ivermectin and G3 - animals treated with carboplatin combined with a metronomic cyclophosphamide (n = 8). Blood was collected from all animals at times 0, 5, 15, 30, 45, 60, 120 and 240 minutes after carboplatin administration. After being harvested …
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The Veron Community Scabies Education and Eradication Program
… the last decade due to the expanded use of oral Ivermectin for the treatment and prevention of ectoparasites such as scabies. Previous research focused on various treatment aspects of the disease, yet most identified the need for basic scabies health education to accompany future studies to …
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Advanced systems for the rapid detection of anthelmintic drugs in food
… (4.0 μg kg-1), thiabendazole (4.2 μg kg-1) and ivermectin (10.2 μg kg-1) residues were determined. The CCβ for carbendazim (50 μg kg-1), 2-aminobenzimidazole (10 μg kg- 1), thiabendazole (10 μg kg-1) and ivermectin (20 μg kg-1) residues were sufficient for the analysis of orange juice. When …
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Skin disorders among schoolchildren in rural Tanzania and an assessment of contributing factors and therapeutic needs
… in the area of Ifakara. Finally, the extent of ivermectin distribution among the study population within the WHO Onchocercosis Control Program (OCP) was checked to assess the influence of this drug on the prevalence of ectoparasitoses. <br>820 primary school children aged 6 to 19 years old were …
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The Pharmacological Characterization of Hco-UNC-49, a GABA-gated Chloride Channel from the Parasitic Nematode Haemonchus contortus
… also observed. For example, the anthelmintics ivermectin and moxidectin both enhanced Hco-UNC-49 GABA responses, while piperazine was able to directly activate Hco-UNC-49 at high concentrations. These results suggest that Hco-UNC-49 is likely an in vivo target for these anthelmintics.
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Exploiting Caenorhabditis elegans as a Discovery Platform to Identify Nematode Parasiticides that Act Through Neuromuscular Disruption
… commercially successful nematode parasiticide ivermectin. Thus, I have identified two novel parasiticide scaffolds that may prove useful for combatting nematode parasites that plague humans.
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Feldur útigangshrossa
… meðhöndluð með lúsasprautu með virka efninu Ivermectin sem fyrirbyggjandi meðferð. Könnunin leiddi í ljós að lítið var um holdhnjúska bæði veturinn 2013-2014 og þar á undan og kom það heim og saman við að veður var fremur hagstætt báða veturna, hiti yfir meðallagi og úrkoma lítil, á þeim …
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Feldur útigangshrossa
… meðhöndluð með lúsasprautu með virka efninu Ivermectin sem fyrirbyggjandi meðferð. Könnunin leiddi í ljós að lítið var um holdhnjúska bæði veturinn 2013-2014 og þar á undan og kom það heim og saman við að veður var fremur hagstætt báða veturna, hiti yfir meðallagi og úrkoma lítil, á þeim …
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Effekten av nematodinfektion på aktivitet och beteende hos förstagångsbetande lamm
… period. Two groups were dewormed with ivermectin (high group) and two groups were untreated (low group). All lambs were fitted with sensors, and the data was downloaded once a week, at the same time with the weighting of animals. Individual faecal samples were collected four times. The …
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Targeting phosphatidylserine exposure in pro-coagulant platelets.
… efficacy at blocking PS exposure in platelets. Ivermectin, clofazimine and benzbromarone had no effect on PS exposure downstream of either thrombin and CRP-XL or A23187 activation. Abamectin and niclosamide treatment caused a modest reduction in the percentage of platelets that exposed PS in …
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The effects of extended-release eprinomectin on heifer performance and fescue toxicity and an evaluation of parasite resistance
… of growing animals when treated with either ivermectin or extended-release eprinomectin. No work has determined the mechanism for this improvement though. The objective of this thesis was to determine if parasite resistance to extended-release eprinomectin was present on a cow-calf operation …
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Stability evaluation of selected anthelmintic macrocyclic lactone compounds and formulations
… compounds such as avermectins (e.g. abamectin, ivermectin, eprinomectin) and milbemycins (e.g. milbemycin oxime and moxidectin) are among most important anthelmintics, used extensively and globally. However, excessive and uncontrolled use of MLs and other anthelmintic classes in the last two …
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