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Showing 1 to 7 of 7 for “"Isoxazolyl"”.
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4-ISOXAZOLYL-1,4-DIHYDROPYRIRINES BIND THE MULTIDRUG-RESISTANCE TRANSPORTER
… have been under intensive investigation. The 4-Isoxazolyl-1, 4-Dihydropyridines (IDHP’s) have been shown to exhibit inhibition of MDR1. A novel series of IDHP compounds have been prepared and found to inhibit MDR1. The synthesis, MDR1 assay results, and relevant controls will be discussed. If …
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4-ISOXAZOLYL-1,4-DIHYDROPYRIRINES BIND THE MULTIDRUG-RESISTANCE TRANSPORTER
… have been under intensive investigation. The 4-Isoxazolyl-1, 4-Dihydropyridines (IDHP’s) have been shown to exhibit inhibition of MDR1. A novel series of IDHP compounds have been prepared and found to inhibit MDR1. The synthesis, MDR1 assay results, and relevant controls will be discussed. If …
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Physiological studies with the experimental herbicide isouron
… herbicide, isouron (N-(5-(1,1-dimethylethyl)-3-isoxazolyl)-N,N-dimethylurea). These studies included two plant metabolites of isouron, a monomethylurea (N-(5-(1,1-dimethylethyl)-3-isoxazolyl)-N-methylurea) and a urea derivative (N-(5-(1,1-dimethylethyl)-3-isoxazolyl)-urea). The compounds were …
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ΜΕΛΕΤΗ ΑΝΤΙΔΡΑΣΕΩΝ ΔΙΑΡΥΛΟΙΩΔΩΝΙΑΚΩΝ ΚΑΙ ΦΑΙΝΥΛΟ(Β-ΑΡΥΛΟΑΙΘΙΝΥΛΟ) ΙΩΔΩΝΙΑΚΩΝ ΑΛΑΤΩΝ
… WITH NITRILOXIDES TO AFFORD PHENYL (SUBSTITUTED ISOXAZOLYL) IODONIUM SALTS. THE CHEMICAL PROPERTIES OF THE CYCLOADDITION PRODUCTS IS BRIEFLY EXAMINED. PHENYL (ARYLETHYNYL) IODONIUM SALTS REACT ALSO WITH NITRONES BUT THE RESULTING PHENYL (SUBSTITUTED ISOXAZOLINYL) IODONIUM SALTS WITH ONE EXCEPTION …
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Synthesis of novel heterocyclic α-amino acids
… Subsequently naphthyl-, pyridyl-, biphenyl- and isoxazolyl- groups were successfully incorporated into the amino acid side chain. The enantiomeric excess of the product amino acids was found to be moderate (10-87%) due to poor diastereoselectivity in the key alkylation step. Moreover, the strict …
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IMPROVED SYNTHESIS OF 3-ARYL-ISOXAZOLES AS INTERMEDIATES FOR NOVEL G-QUADRUPLEX BINDING ANTI-TUMOR AGENTS
… specific towards cancer cells. Anthracenyl isoxazolyl amides (AIMs) have shown potent anti-tumor activity and have evidence to support them as G4 binding molecules. Studies of the AIMs’ unique mechanism of action require an efficient synthesis of target molecules. For our system, methods …
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IMPROVED SYNTHESIS OF 3-ARYL-ISOXAZOLES AS INTERMEDIATES FOR NOVEL G-QUADRUPLEX BINDING ANTI-TUMOR AGENTS
… specific towards cancer cells. Anthracenyl isoxazolyl amides (AIMs) have shown potent anti-tumor activity and have evidence to support them as G4 binding molecules. Studies of the AIMs’ unique mechanism of action require an efficient synthesis of target molecules. For our system, methods …