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Showing 1 to 20 of 53 for “"Isoflavone"”.
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The anti-diabetic mechanisms by isoflavone genistein
Diabetes is growing public health problem in the United States. Both in Type 1 and Type 2 diabetes, the deterioration of glycemic control over time is largely due to insulin secretory dysfunction and significant loss of functional β-cells. As such, the search for novel agents that promote β-cell …
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The Effects of Isoflavone Supplementation on Rats and Humans
Isoflavones have antioxidant activities in vivo, however, their antioxidative potential against oxidative stress initiated by exercise was not explored. The first study investigated the effect of high-genistin isoflavone (HGI) supplementation on erythrocyte antioxidant enzymes and tissues' …
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The Soy Isoflavone, Genistein, as a Modulator of Intestinal Development
In summary, genistein at concentrations currently present in soy infant formulas inhibited intestinal cell proliferation both in vitro and in vivo, which may have implications for the intestinal health of infants and requires further investigation.
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Soy Isoflavone Supplementation Does Not Alter Lymphocyte Proliferation and Cytokine Production In Postmenopausal Women
… body of evidence has demonstrated that soy isoflavone consumption may protect against the development of various chronic diseases. This protection could be linked to isoflavone-induced alterations in immune function. However, recent in vitro and animal studies suggest that soy isoflavones …
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The effect of soy isoflavone intake on cardiovascular disease risk factors - potential role of equol
Isoflavones, the subclass of flavonoids found in soybeans, may reduce the risk of cardiovascular disease (CVD). However, the current evidence is inconsistent. The capability to produce the isoflavone metabolite equol in 20-60 % of the population might underlie the benefits of isoflavone intake on …
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The effect of isoflavone supplementation on cardiovascular disease parameters in men undergoing 80% VO₂pk exercise
… with diseases influenced by oxidative stress. Isoflavones found in soy, such as genistein and daidzein are reported to have potent antioxidant properties and have been shown to inhibit LDL oxidation in vitro. Although there is a strong base of data that supports the correlation between soy …
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Soy Isoflavone Supplementation Does Not Alter Distribution of Circulating Lymphocytes or Natural Killer Cell Activity in Postmenopausal Women
… body of evidence has demonstrated that soy isoflavone consumption may protect against the development of various chronic diseases. This defense could be linked to isoflavone-induced alterations in immune function. However, to date, no study has examined the effect of soy isoflavone …
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Bifidobacterial enzymic transformation of isoflavones, their bioavailability and effects on disease risk biomarkers in postmenopausal women
… soymilk, contain only 5 to 10% of total isoflavone in a biologically active aglycone configuration, with the remainder found as isoflavone glucoside conjugates. Saccharolytic enzyme-producing Bifidobacterium, classified as probiotics, are commonly incorporated into fermented milk products …
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Isotopic labeling of isoflavones from plant cell and organ culture for metabolic tracking in animal models
Kudzu and red clover isoflavones are phytoestrogens that have been investigated as alternatives to estrogen replacement for treatment of osteoporosis, cardiovascular disease, and neurological disorders. However, the pharmacokinetics of these compounds are not clearly understood. In the present …
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Stability of bioactive isoflavones and glycolytic enzymes produced by probiotic bacteria in soy based food during processing and storage
… used in the bioconversion of the predominant soy isoflavone glycosides to their bioactive aglycone forms. Fifteen probiotic micro-organisms that included Bifidobacterium sp., Lactobacillus acidophilus and Lactobacillus casei were screened for β-glucosidase activity using ρ- …
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Development of a standardized functional soy product for cancer prevention trials:Phase II evaluation of isoflavone bioavailability in men with asymptomatic prostate cancer
<p>Soy isoflavones have generated substantial interest in the last few decades. However, bioavailability, metabolism, bioactivity and structural fate of isoflavones have been the subject of much stimulating discussion. Of the many dietary variables of interest, diets rich in soy foods are …
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The effects of dietary soy isoflavone supplementation on carcass cutability and meat quality of pigs infected with porcine reproductive and respiratory syndrome virus
… syndrome virus (PRRSV) infection and dietary soy isoflavone (ISF) supplementation on carcass cutability and meat quality of commercial pigs. Barrows were randomly allotted to experimental treatments that were maintained throughout the study: non-infected pigs received an isoflavone-devoid control …
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Characterization of antioxidant activities of soybeans and assessment of their bioaccessibility after in vitro digestion
… compared for their antioxidant properties and isoflavone profiles. The extracts were evaluated for their total phenolic contents (TPC), Oxygen Radical Absorbance Capacity (ORAC), and DPPH™ radical scavenging activities. In order to evaluate efficient preparation methods for soybean …
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The effect of dietary genistein on breast cancer metastasis
The dietary isoflavone supplements are now perceived as safe and a natural alternative to hormone replacement therapy (HRT) and are recently being consumed by postmenopausal women. However, as weak estrogens, isoflavones may have the potential to alter breast cancer (BC) growth and metastasis which …
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Global Expression Profiles and Targeted Pathway Modulation During Soybean Embryo Development
… over the control seeds, but no change in isoflavone content, and is a candidate for more extensive profiling of flavonoid compounds.
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The Isolation of Natural Products From Plant Extracts
… of the weakly cytotoxic biochanin A (an isoflavone compound). The bioassay of three mutant yeast strains (1138, 1104, and 1353) directed the isolation of DNA-damaging alkaloids from Solanum hostmannii. These alkaloids were identified as verazine and (20R) epimer verazine. In addition, …
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Soybean Responses to Atmospheric Increases in Carbon Dioxide and Ozone
… to seed C content but not to seed N. Total seed isoflavone content response to treatments was cultivar-dependent, with elevated [CO2] causing an increase in Dwight and Loda and elevated [O 3] causing a decrease in Corsoy and Loda. Isoflavone concentration also varied among the years of …
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Enhanced β-galctosidase activity in probiotics for improved bioconversion of soy isoflavones in dairy and soy-based yoghurt
… produced by LB and BB12 in biotransformation of isoflavone glycosides (IGs) to aglycones (IAs).
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Toxizität und Gentoxizität von Phytohormonen und deren Metaboliten
… sind die Phytoöstrogene aus den Stoffgruppen der Isoflavone, Cumestane und Indol-3-carbinole. Weit über 100 Pflanzen produzieren Phytohormone. Die bekanntesten sind die Sojabohne, Weintrauben, Leinsamen, Haferflocken, Spargel, Traubensilberkerze und roter Klee. Phytohormone können täglich in …
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