Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Iso-1-cytochrome c"”.
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Thermodynamics and Kinetics of Iso-1-cytochrome c Denatured State
… simple loops in the denatured state using c-type cytochromes. New insights into how the properties of these loops impact the denatured state are outlined in this thesis. First, studies on a 22-residue loop revealed a previously unreported finding that equilibrium loop formation was not strongly …
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Conformationally gated electron transfer studies of iso-1-cytochrome c
… funnel. Histidine-heme alkaline conformers of cytochrome <italic>c</italic> are used as a model for a late folding intermediate or partially unfolded state that can be exploited to study roughness near the bottom of a folding funnel.<p> In my thesis work, I have developed a novel method using …
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Thermodynamics and Kinetics of Iso-1-cytochrome c Denatured State
… simple loops in the denatured state using c-type cytochromes. New insights into how the properties of these loops impact the denatured state are outlined in this thesis. First, studies on a 22-residue loop revealed a previously unreported finding that equilibrium loop formation was not strongly …
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Conformationally gated electron transfer studies of iso-1-cytochrome c
… funnel. Histidine-heme alkaline conformers of cytochrome <italic>c</italic> are used as a model for a late folding intermediate or partially unfolded state that can be exploited to study roughness near the bottom of a folding funnel.<p> In my thesis work, I have developed a novel method using …
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Rational Design of Chemotherapeutic Agents by Quantitative Structure-Activity Relationships and Solution NMR Methods for High Resolution Protein Structure Refinement
… 13C, 15N-labeled Saccharomyces cerevisiae iso-1 cytochrome c was overexpressed in Escherichia coli and purified in its ferric form for NMR studies. The chemical shifts of most of the 1H, 13C, and 15N nuclei were assigned for future analyses of the incorporation of 13Calpha chemical shift, …
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THERMODYNAMIC AND KINETIC PROPERTIES OF CYTOCHROMES C AND C’ IN THE DENATURED STATE: PROPENSITY FOR RESIDUAL STRUCTURE
… of the third helix (positions 83 and 87) in cytochrome c’ (Cytc’) and have measured histidine-heme loop formation in 3 M gdnHCl. A series of thirteen variants that include the A83S/A87S substitutions have been engineered with single surface histidine substitutions to provide a range of …
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THERMODYNAMIC AND KINETIC PROPERTIES OF CYTOCHROMES C AND C’ IN THE DENATURED STATE: PROPENSITY FOR RESIDUAL STRUCTURE
… of the third helix (positions 83 and 87) in cytochrome c’ (Cytc’) and have measured histidine-heme loop formation in 3 M gdnHCl. A series of thirteen variants that include the A83S/A87S substitutions have been engineered with single surface histidine substitutions to provide a range of …