Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"Ischaemic heart disease"”.
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PHARMACOLOGICAL MODULATION OF THE ADAPTIVE IMMUNE SYSTEM IN ISCHAEMIC HEART DISEASE
Inflammation plays a key role in the disease processes of both atherosclerosis and myocardial infarction (MI). Regulatory T (Treg) cells are a subset of the adaptive immune system involved in immune tolerance. Animal models show that increasing Treg cell numbers in atherosclerosis can limit disease …
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An evaluation of cardiac services in four hospitals in Lancashire for patients with ischaemic heart disease
The aim of this study was to develop and manage a system measuring and linking morbidity and mortality in relation to care provision for patients with myocardial infarction (MI) in four hospitals in Lancashire, UK. Five data sources were used; Initially research nurses recorded hospital data from a …
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The Epidemiology and Management of Ischaemic Heart Disease in New Zealand: A Series of National Routine Health Data-Linkage Studies
… that examined the epidemiology and management of ischaemic heart disease (IHD) in New Zealand over the last 12 years. Using individual-level linkage of routinely collected national data on almost the entire population, the first three studies investigated long-term statin use, acute …
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The relationship between the hardness of potable water and cardiovascular and ischaemic heart disease mortality in South African urban areas
… between death rates from cardiovascular disease (CVD) or ischaemic heart disease (IHD), and the hardness of local water supplies, a phenomenon which is known as the "water story". These findings have not, however, been universal and it was decided that a study carried out in South Africa …
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Metabolic and endocrine aspects of coronary disease
… the incidence of coronary atherosclerosis and ischaemic heart disease have been reviewed. Evidence has been presented to suggest that there are aetiological factors which favour the development of ischaemic heart disease without influencing the incidence of coronary atherosclerosis. The close …
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The composition of certain lipids in man : a comparative study of lipids in total serum, in the serum B-lipoprotein fraction and in arterial atheromatous plaques in certain groups of people
… role in research into the pathogenesis of ischaemic heart disease. A large number of these studies have been concerned with the relationship between serum lipids and ischaemic heart disease (I.H.D.), which has been defined by the World Health Organization (1957) as "the cardiac disability, …
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Development and assessment of supercharged platelets as a novel drug delivery mechanism for promoting cardiac regeneration
Ischaemic heart disease is the leading cause of death globally, with post-myocardial infarction heart failure significantly reducing quality of life and life expectancy. Current treatment strategies focus primarily on alleviating symptoms and reducing the burden on the damaged heart, failing to …
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Regulation of plasma triglyceride metabolism : some nutritional and endocrine effects
… elevation of plasma lipids and lipoproteins, and ischaemic heart disease (IHD). Despite many years of study iri this field, the nature of this association is still poorly understood. The exact mechanism whereby plasma lipids and lipoproteins influence the pathogenesis of atherosclerosis still …
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Clinical characteristics, causes, adherence to heart failure treatment guidelines and mortality of patients with acute heart failure: the Groote Schuur Hospital experience
Background: There is limited information on acute heart failure (AHF) and the treatment thereof in sub-Saharan Africa. Therefore, the aim of this study was to describe the clinical characteristics, causes, adherence to heart failure (HF) treatment guidelines and mortality of patients presenting to …
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Attributable Healthcare Costs of Diabetes Complications in Alberta Adults: A Longitudinal Retrospective Cohort Analysis
… examined included myocardial infarction, stroke, heart failure, end-stage renal disease, blindness, other chronic ischaemic heart disease, diabetic foot ulcer, and lower-limb amputation. Attributable costs were estimated using recycled predictions, adjusting for age, sex, comorbidity burden, and …
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Familial hypercholesterolaemia - the Cape Town experience
… of the pathology and complications of the disease. Demographics of patients attending the clinic, their clinical signs, lipid profiles and complications are analysed in the context of different ethnic origins and genetic defects. Lipoproteins, especially low density lipoprotein particle …
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Targeting Inflammation in Atherosclerosis: The Role of Low-dose Interleukin 2 in Acute Coronary Syndromes
… have improved CV outcomes in patients with ischaemic heart disease (IHD).4 5 However, these have come at a cost due to serious, and at times, fatal, side-effects as a result of immunosuppression. Furthermore, there was no difference in all-cause mortality between treatment agents and …
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Redefinition of uraemic cardiomyopathy with cardiac magnetic resonance imaging
Patients with end stage renal disease (ESRD) have a 20-100 fold risk of premature cardiovascular death compared to age matched controls from the general population. These patients have many ‘conventional’ cardiovascular risk factors such as diabetes, ischaemic heart disease, hypertension, cigarette …
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Image processing techniques in nuclear medicine
… with occult metastases from those without liver disease. <br></br><br></br>A fully automatic algorithm to derive a left ventricular edge from each frame of an ECG gated cardiac blood pool study was developed and validated in patient studies. Left ventricular ejection fractions calculated from …
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Healthy Satiety Effects of Paleolithic diet on Satiety and Risk factors for Cardiovascular disease
The prevalence of cardiovascular diseases (CVD) exhibits considerable variation across agrarian societies, whereas they are virtually absent in non-agrarian societies such as hunter-gatherer and horticultural societies. When looking for lifestyle factors which could promote CVD, it therefore seems …
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The effect of allopurinol on left ventricular mass in haemodialysis patients
… of death amongst patients with end stage renal disease. Increased left ventricular mass (LVM) is strongly associated with all-cause and cardiovascular mortality. Reduction of LVM may improve outcomes. Allopurinol has reduced LVM in randomised controlled trials in chronic kidney disease, diabetes …
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The prevalence of dysbetalipoproteinaemia in Ghanaian adults living in Accra
… associated with premature cardiovascular disease. In several places worldwide, especially in sub-Saharan Africa, clinicians often miss the diagnosis of dysβ due to a lack of awareness of the disorder and its manifestations. Although the apo E2/2 isoform is the most common genetic cause of …
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Coronary heart disease and hydrogenated fat; an investigation of the levels of chemically-modified fats on adipose tissue
… at post mortem examination from persons dying of ischaemic heart disease (cases) and the remainder from persons dying from unrelated causes (controls). After due matching for area of residence, it is shown that the case specimens had a significantly lower proportion of Land a higher proportion of …
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