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Showing 1 to 3 of 3 for “"Iron-Dextran"”.
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IRON OVERLOAD AND BIRTH DEFECTS
Large, intravenous doses of iron-dextran are teratogenic in a number of laboratory species (M Phil). To elucidate the mechanism, studies were performed in rats and rabbits to identify possible maternal, placental and foetal sites of action. Maternal toxicity, manifested by bodyweight depression, …
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Novel Delivery Systems For Iron Replenishment
<p>Iron is an integral part of hemoglobin and essential for the production of red blood cells. Iron deficiency and the resulting anemia are major nutritional deficiency disorders. The majority of patient populations suffering from iron deficiency anemia (IDA) are women of child bearing age and …
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Metabolism of supplemental iron by hepatic parenchymal and sinusoidal cells of the neonatal pig
… and intracellular metabolism of supplemental iron. Hepatocytes were prepared from collagenase perfused livers by differential centrifugation, while Kupffer cells and endothelial cells were isolated by centrifugal elutriation. One day old piglets were injected with iron-dextran (Fe-dextran) and …