Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Ionizing radiation-induced foci (irif)"”.
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Identification and Characterization of Novel Kinases that Regulate BRCA1 Expression and Function
… to localize to sites of DNA damage and form ionizing radiation-induced foci (IRIF), to screen a kinase siRNA library and thirty-two potential positive regulators of BRCA1 were identified. Subsequent validation resulted in fourteen kinases that consistently diminished BRCA1 IRIF. Secondary …
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Study of the DNA Damage Complexes Within the HTLV-1 Tax Oncoprotein Interactome
… repair (DDR) protein that is found in nuclear foci called ionizing radiation-induced foci (IRIF) that form in response to DNA damage. In this study we show that MDC1, which is a part DNA-PK-MDC1 signaling pathway, is active in Tax expressing cells. In addition, we demonstrate that Tax recruits …