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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 51 for “"Ionising radiation"”.
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The effects of ionising radiation on polypropylene
The interaction of ionising radiation with polymers is described and the literature relating; to the effects on polypropylene is reviewed. Oxidative and free radical reactions are discussed with particular reference to post-irradiationeffects.Isotactic and atactic polypropylene were δ and electron …
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Quantification of complex DNA damage by ionising radiation: An experimental and theoretical approach
Ionising radiation potentially produces a broad spectrum of damage in DNA including single and double strand breaks (ssb and dsb) and base damages. It has been hypothesised that sites of complex damage within cellular DNA have particular biological significance due to an associated decreased …
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Shedding Light on the Biological Effects of Ionising Radiation on DNA Using Advanced Optical Microscopy
Detrimental effects of ionising radiation (IR) stem from its unique ability to produce clustered DNA damage (CDD) and double-strand breaks (DSBs). CDD consists of two or more lesions in close proximity, including DSBs, single-strand breaks and/or base damages. CDD complexity increases with rising …
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Computer modeling and experimental work on the astrobiological implications of the martian subsurface ionising radiation environment
… zone, a major environmental hazard is the ionising radiation field generated by the flux of exogenous energetic particles: solar energetic protons and galactic cosmic rays. The research reported here constitutes the first multidisciplinary approach to assessing the astrobiological impact of …
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Trainee teachers and ionising radiation: understandings, attitudes and risk assessments. A descriptive study in one institution
… of and attitudes to radioactivity and ionising radiation, in one School of Education. The investigation addressed three research questions. The first focussed on the understanding of alpha, beta and gamma radiations. The second looked at risk assessments involving alpha, beta and gamma …
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Radiation Shielding calculations using MCNPX transport code for cost optimization of the shielding material to be used at iThemba LABS.
… has a potential of producing strong sources of ionising radiation. The most challenging entities, which are part of the indirect ionising radiation, are neutral neutrons and photons. There is a need to protect humans and materials from ionising radiation by providing adequate shielding to …
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The role of linker histone variant in double strand break repair
… levels of un-repaired DSBs following exposure to ionising radiation. This linker histone variant interacts with both DNA ligase IV and XRCC4 in vivo, along with DNA-PK, the KU complex and nucleolin. Interestingly, the interaction with nucleolin only occurs in the presence of DNA damage following …
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Solid-phase combinatorial chemistry and scintillation proximity assays
… the ability to scintillate in the presence of ionising radiation. In addition, the molecules were incorporated into liposomal preparations which were subsequently evaluated for the ability to scintillate in the presence of ionising radiation. The optimal liposomal preparation was introduced …
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On a dual wavelength optical sensor system for measuring strain and temperature simultaneously in tokamak port plug
… will be affected by temperature changes and ionising radiation (neutrons produced by the burning plasma); it is therefore necessary to instrument the structure with long lasting, accurate, temperature and strain monitoring devices. This thesis demonstrates that using electrical sensors in the …
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Transcriptomic and Secretomic Profiling of Isolated Leukocytes Exposed to Alpha-Particle and Photon Radiation - Applications in Biodosimetry
The general public is at risk of ionising-radiation exposure. The development of high-throughput methods to triage exposures is warranted. Current biodosimetry techniques are low-throughput and encumbered by time and technical expertise. Although there has been an emergence of gene-profiling tools …
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Cell-type-specific responses to DNA damage from acute and chronic radiation
It is well understood that radiation causes damage to DNA, which triggers a DNA-damage response often centred on the signalling pathways of ATM, with the subsequent involvement of proteins such as p53, p21 and H2AX. Many experiments have been performed with cell lines derived from different origins …
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Occupational hazards and radiation safety in veterinary practice including zoo veterinary practice in Australia
… The prevalence of physical hazards including radiation, chemical and biological hazards reported by veterinary practitioners and the author's own experience as a veterinary practitioner, chairman of the safety committee, member of the animal ethics committee and manager, research In the …
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Exploring poly (2, 5) benzimidazole enhanced with carbon nanotubes for space applications
… explores using polymeric materials for space radiation shielding in low-earth orbit. Shielding against radiation is essential on any space mission. Low atomic number materials, such as hydrogen, have shown to be effective in shielding ionising radiation. However, compared to metallic alloys, …
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Overcoming wound healing complications following radiotherapy in human breast dermal fibroblasts, through the influence of preadipocytes from the stromal vascular fraction
… benefits for cancer patients, but ionizing radiation causes damage of surrounding healthy tissues with poor wound healing a common side effect. Therefore, further oncoplastic, reconstructive surgery is challenging and often problematic. Current research models use normal human dermal …
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Radiation damage effects in charge coupled devices
The effects of Sr90 beta radiation and Co60 gamma radiation on the operation of EEV buried channel charge coupled devices (CCDs) have been studied. This work was instigated by the need to qualify CCDs for the SLD vertex detector. However, the work is also relevant to other small signal, low noise …
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An investigation of radiolytic damage to biomolecules in foodstuffs
… of an effective test system for detecting the irradiation status of foodstuffs is essential for the establishment of legislative control and consumer choice. For foodstuffs consisting mainly of water, treatment with ionising radiation initially generates highly reactive free radical species …
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Evaluation of diamond-like carbon films for lubrication in space
… an absent of gravity, a lack of oxygen, and ionising radiation. Currently, sputtered molybdenum disulfide (MoS2) is an established solid lubricant for space applications. However, diamond-like carbon coatings have been increasingly studied as potential candidates for preparation of wear …
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Photodynamic Therapy utilizing Interstitial Light Delivery Combined with Spectroscopic Methods
… from serious disadvantages. The treatments, e.g. ionising radiation, chemotherapy, surgery, may themselves induce malignancies or the patient may be physically impaired for a longer period of time. The work presented aims at developing equipment and methods that use light for both detection and …
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Social and scientific issues in the acceptibility of radiation risks
Ionising radiation hazards are perhaps the most documented and regulated occupational and environmental hazard. In the radiological protection field a single expert advisory organisation has had an unusually large influence on the international standard setting process. This is the International …
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Optimization of Gold Nanoparticles for Radiotherapy
… with high atomic number (Z), that interact with ionising radiation to generate secondary electrons and reactive species that increase cellular damage. One of the most promising elements to use is gold, in the form of gold nanoparticles (AuNPs) because of its biocompatibility and amenability to …
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