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Showing 1 to 1 of 1 for “"Ionisable amino-polyesters"”.
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Design and synthesis of ionisable amino-polyester lipid nanoparticles for extrahepatic RNA delivery
… (ROP), can help overcome these limitations. Ionisable amino polyesters (APEs) synthesised via ROP and co-formulated with lipids into nanoparticles (APE-LNPs) have demonstrated selective mRNA delivery to non-liver tissues. In the first part of this work, 36 ionisable APEs were synthesised to …