Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Ion Channel Modulation"”.
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Ion channel modulation during Chlamydia trachomatis development
… causes sexually transmitted and ophthalmic infections (trachoma) in humans. C. trachomatis resides within a specialised membrane-bound replicative compartment termed the inclusion and exhibits a biphasic lifecycle requiring interconversion between two bacterial forms, infectious non-replicative …
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NOVEL THERAPEUTIC APPROACHES EMERGING FROM HCN CHANNELS STRUCTURAL AND FUNCTIONAL STUDIES
Hyperpolarization-activated cyclic-nucleotide gated 1 (HCN1) channels are the molecular determinants of the cationic Ih current that regulates spontaneous electrical activity and synaptic integration in neurons. Mutations in the HCN1 gene have been linked to Early Infantile Epileptic Encephalopathy …
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Functional Studies of Novel Bioactives From Complex Host-Microbiomes as Drug Leads for Cancer, Infectious Disease, Depression and Pain
… particularly those involving diseases or conditions that affect large numbers of the human population. It is difficult to point directly to one factor leading evolution of the process but the definition of a mechanism of pharmacological action for a drug lead has noticeably become a higher …