Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 63 for “"Intravenous Injection"”.
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Biodistribution Studies of 64Cu-DOTA-Cetuximab after Intraperitoneal and Intravenous Injection in a Malignant Ascites Mouse Model of Human Gastric Carcinoma
… factor receptor (EGFR) was established by SQ injections of NUGC-4 and MKN-45 gastric cancer cells into either shoulder of female BALB/c nude mice. The MA model was produced by i.p. injection of NUGC-4 cells. Cetuximab was conjugated to a bifunctional chelator (p-SCNBn- DOTA) and labeled with …
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The Effects of Methotrexate on Rat Parotid and Submandibular Glands and Their Secretions (Antineoplastic, Protein, Salivary, Amylase Catecholamines)
… cannulated and saliva flow was evoked by either intravenous infusion of acetylcholine (10 to 100 (mu)g/min) or an intravenous injection of bethanechol (100 (mu)g/kg).
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Evaluation of Practical Exercises Using an Intravenous Simulator Incorporating Virtual Reality and Haptic Technologies
… reality/haptic technology applied simulator on intravenous injection education to students in college of nursing. The experiment was subjected to 119 randomly selected freshman students divided in 3groups from college of nursing of a university: IV Arm Group, utilizing a conventional arm model …
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A compatibility study of common additives in protein hydrolysate-dextrose solutions for parenteral hyperalimentation
… normally provided in the diet.</p><p>The intravenous route of administration is generally recognized as the most effective means of systemic administration. Yet, considering the other routes used clinically, it is of relatively recent development. Parenteral therapy began in 1616 with the …
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Peripheral Blood Mononuclear Cells Cytokine Expression in Horses Treated with Dexamethasone
… 0.1 mg/kg of dexamethasone sodium phosphate by intravenous injection once daily for 5 days. Group II (8 horses) received an equivalent volume of sterile saline by intravenous injection daily for 5 days. A sample of 5x10 mililiters of blood in acid citrate dextrose was obtained prior to initial …
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A computational model for transdermal diffusion of lidocaine and tetracaine topical patches
… drug delivery systems such as oral medicine and intravenous injection. In order to reach the circulatory system of the human body, drug molecules have to pass through the epidermis (outer layer) of the skin. The barrier properties of epidermis originate from low permeability of stratum corneum …
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Preclinical Study of Potential Antiglioma Novel Tetrahydroisoquinoline Analogs: Pharmacokinetics and Mechanism of Action
… In male Sprague Daley (SD) rats, after 10 mg/kg intravenous injection, total body clearance (CL) of EDL-291 was 209 mL/min/kg (CV 23.7%), 39% lower than EDL-155 but still much higher than rat liver blood flow. 1.2% of dosed EDL-291 was found in urine (fe) over the 24 hr post-dose period. EDL-291 …
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ROLE OF HYDROCORTISONE 21-HEMISUCCINATE DURING CARRAGEENAN-INDUCED ACUTE INFLAMMATION
… on acute inflammation induced by carrageenan. Intravenous injection of hydrocortisone 21-hemisuccinate resulted in a significant drop in circulating blood leucocytes, with a parallel decrease in the adhesiveness of these cells. Such observations may account for the significant reduction in the …
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Calcium-boro-saccharate-gluconate: studies of preparation, toxicology and effect on serum calcium level in cows
… and no more toxic for cows, when injected intravenously, than is the commercial product, Calcium-Boro-Gluconate. 4. The intravenous injection of either of these solutions into cows causes an immediate, marked rise in the serum calcium level. This rise is followed by a rapid drop, and, in …
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Quantification of regional perfusion, shunt fraction and ventilation using positron emission tomography : a nonlinear tracer kinetics model
… tracer 13N2 as measured by PET following a rapid intravenous injection of a bolus of 13N2 in saline solution. The model is made of a compartment representing the right heart and pulmonary vasculature through which the tracer is mixed and diluted in blood. From this compartment, blood is …
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Efficacy of the Bromsulfophthalein (BSP) 30-Minute Retention Test for the Diagnosis of Hepatobiliary Disease in Dogs
… (BSP) retained in serum 30 minutes after intravenous injection can be used to evaluate hepatic function. BSP retention of less than 5% 30 minutes after intravenous administration is considered normal in dogs. The BSP retention test fell out of favor due to perceived inaccuracy when …
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The Biomedical Applications of Protein Microspheres
… microsphere diameter (<5 microns) permitted the intravenous injection of microspheres, while the use of native protein in forming the microspheres prevented any significant immune response. We have synthesized microspheres that can be monitored with in vivo imaging techniques (MRI or X-ray) and …
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Liposome Encapsulated Manganese Chloride as a Liver Specific Contrast Agent for Magnetic Resonance Imaging
… liposomes were concentrated in the liver after intravenous injection. Uptake of the vesicles into tumors was shown to be negligible. This suggested the possibility that the differences in uptake of the Mn$\sp{2+}$ in liposomes between liver and tumor might provide a means of highlighting tumors …
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Experimental infection with Sarcocystis neurona alters the immune response: the effect on CD4+, CD8+, B-cell, monocyte and granulocyte populations in horses
… Five horses were challenged for ten days via intravenous injection of autologous lymphocytes infected with S. neurona. Neurologic parameters of all horses were assessed for 70 days following infection. Immune function was based on proliferation responses to mitogens, as assessed through …
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Annexin A5-Conjugated Polymeric Micelles For Dual Spect and Optical Detection of Apoptosis
… fluorescence molecular tomography (FMT) after intravenous injection of <sup>111</sup>In-labeled Annexin A5-CCPM in 6 different apoptosis models. In contrast, there was little signal in respective healthy tissues. All the biodistribution data confirmed imaging results. Moreover, histological …
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The Development and Use of an Intraoral Force Transducer in the Diagnosis and Treatment of Myasthenia Gravis
… using it diagnostically in conjunction with the intravenous injection of an anticholinesterase drug (Tensilon). Twenty-three known myasthenic patients were tested, as well as nine normal individuals. This examination consisted of a battery of tests to determine the subjects’ incisive biting …
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Hyperpolarized Carbon-13 Magnetic Resonance Measurements of Tissue Perfusion and Metabolism
… removed from the polarizer and administered by intravenous injection. Specialized imaging strategies are therefore needed to extract as much information as possible from the HP signal during its limited lifetime.</p> <p>In this work, we present innovative strategies for measurement of tissue …
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Hepatitis B Virion and cccDNA Formation in Primary Tupaia Hepatocytes and Human Hepatoma Cell Lines upon HBV Genome Transduction with Replication-defective Adenovirus Vectors and in vivo Infection of Tupaias
… were infected with recombinant adenoviruses by intravenous injection. In two of the newborn animals, HBV antigens and HBV virions were detectable for more than 4 months. As in transduced PTHs, in vivo infection was dose dependent and subject to dynamic changes. It seems that newborn tupaias are …
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The Role of Qa-2, the Functional Homolog of HLA-G, in a Mouse Model of Behcet's Disease Induced by HSV Inoculation
… those without ocular symptoms. Silencing Qa-2 by intravenous injection of siRNA (500 nmol/mouse, 4 times with 3-day intervals) specifically reduced Qa-2 levels and resulted in BD progression, with the development of symptoms, including ocular symptoms and arthritis. We demonstrated that this …
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