Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Intranasal immunization"”.
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Intranasal Immunization of Pigs with Porcine Reproductive and Respiratory Syndrome Virus like Particles Plus 2’, 3’ –cGamp Vaccigrade™ Adjuvant Exacerbates Viremia After Virus Challenge
… adjuvant against pigs infected with PRRSV after intranasal immunization to evaluate the immune response and protective efficacy by the VLPs and adjuvant. The VLPs contain PRRSV nucleocapsid (N), glycoprotein 5 (GP5), membrane (M), and the envelope (E) proteins. There were 3 groups of pigs …
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Novel intranasal GNRs-DNA vaccines against human papillomavirus infection
… the murine bone marrow-derived macrophages cell. Intranasal immunization ofBALB/c mice with GNRs-DNA resulted in YFP expression in nasal and lung tissuesin one day. Three doses (3 × 480ng plasmid DNA per mouse) elicited neutralizingantibodies in the serum and antibody secreting cells in spleen …
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Mechanisms Involved in Enhanced Protection Against Gram Negative Bacterium Francisella tularensis Utilizing an FcR Targeted Vaccine Platform
… F. tularensis (iFt) to Fcγ receptors (FcγRs) via intranasal immunization with mAb-iFt complexes reverses the anti-inflammatory effects of the bacterium on macrophages by ix down-regulating production of IL-10 and mediates generation of F. tularensis-specific, IFN-γ secreting effector memory CD4+ T …
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The Influence of Immunization Route On The Adjuvant Effect of Alpha-Galactosylceramide
… antigens. While a single intravenous immunization of α-GalCer strongly activates NKT cells, multiple doses by this route are well documented to induce anergy in NKT cells. Anergy is defined as the deficiency in NKT proliferation and cytokine production, including IL-4 and IFNγ. …
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Characterization of Alpha-Galactosylceramide As A Mucosal Adjuvant
… immune responses to antigens, particularly for immunizations targeting the tolerogenic mucosal tissues, which are more biologically relevant for protective immunity against pathogens transmitted by the mucosal routes. Adjuvants possess the inherent capacity to bridge innate and adaptive immune …