Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Intranasal drug delivery"”.
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Study of the enhancement effect of cyclopentadecanolide on protein permeation through lipid membranes
<p>Intranasal drug delivery has been a topic of increasing interest for a decade as a convenient and reliable method for the systemic administration of drugs. The low bioavailability of simple formulation of protein drugs, such as insulin, can be greatly improved by using permeation enhancers. We …
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Two-Part Reactive Formulations for Intranasal Delivery of Benzodiazepines
… diazepam. Despite the effectiveness of these drugs, the delivery routes are not ideal for first-line, outpatient treatments. A skilled caregiver must be present to administer drugs intravenously, and the social stigma associated with rectal administration results in low compliance. Intranasal …
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Development of implantable devices for schizophrenia treatment
… of neurotransmitters in the brain. One of the drugs that is commonly prescribed to treat schizophrenia is risperidone (RIS). This drug is administered through the oral route (e.g. tablets). Accordingly, the drug is exposed to first-pass metabolism and enzymatic degradation in the …
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Microfluidic-generated Double Emulsions for Cell Study, Drug Delivery and Particle Therapeutics Fabrication
… we will show the successful application of DE as drug carriers for intranasal drug delivery. In chapter 5, we showed the application of microfluidics generated DE as template for microparticle synthesis and the use of these microparticles as therapeutic agents in nucleic acid induced inflammations …
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Gelatin nanoparticles for improved neuroprotection of intranasally delivered osteopontin in ischemic stroke
Delivery of therapeutic agents to the brain is significantly hampered by the blood- brain barrier (BBB). Typically, only small, lipophilic molecules can freely enter the brain parenchyma following systemic administration. During the initial development phases, many drug candidates for neurological …