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Showing 1 to 12 of 12 for “"Intestinal smooth muscle"”.
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Epigenetic Modification of Phenotype in Intestinal Smooth Muscle Cells
Inflammation causes proliferation of intestinal smooth muscle cells (ISMC), contributing to the thickened intestinal wall and the dysmotility symptoms observed in inflammatory bowel disease (IBD). A unique consequence of Crohn’s disease (CD), a subset of IBD characterized by chronic, transmural …
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Some Ultrastructural and Mechanical Studies on Cat Intestinal Smooth Muscle
Made available in DSpace on 2015-05-12T21:45:08Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7013421.PDF: 6948571 bytes, checksum: a814f05b3936756f3f57ec14a128796b (MD5) Previous issue date: 1969
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Electrical Properties and the Sodium, Potassium, and Chloride Content of Intestinal Smooth Muscle Cells
Made available in DSpace on 2014-12-05T22:14:39Z (GMT). No. of bitstreams: 1 5900469.pdf: 4006299 bytes, checksum: 5200802e70074f1d4c614d25da06996e (MD5) Previous issue date: 1958
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Inflammation Promotes the Processing of Glial Cell-Line Derived Neurotrophic Factor by Matrix Metalloproteinase-9 in Intestinal Smooth Muscle Cells
The control and regulation of all major intestinal functions are coordinated by neurons within the enteric nervous system (ENS). While intestinal inflammation initially causes a profound loss of enteric neurons, the ENS demonstrates remarkable changes in neuronal structure and function to retain …
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Studies on the mechanism of action of the bioflavonoid Hesperidin methyl chalcone in causing vascular and intestinal smooth muscle to relax
… hesperidin methyl chalcone (HMC), in causing smooth muscle to relax. The term bioflavonoid refers to several compounds that can be extracted from the mesocarp of citrus fruits. They have been the subject of investigation and controversy since 1936. Much of this is covered in a eview by Vogin …
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Differentiation and contractility of colon smooth muscle under normal and diabetic conditions
Intestinal smooth muscle development involves complex transcriptional regulation leading to cell differentiation of the circular, longitudinal and muscularis mucosae layers. Differentiated intestinal smooth muscle cells express high levels of smooth muscle-specific contractile and regulatory …
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Neuroglial differentiation and neo-innervation in extracellular matrix-based tissue engineered innervated smooth muscle sheets
… enteric nervous system regulate and coordinate smooth muscle motility. Enteric neurons and glia of the myenteric plexus are organized into ganglia, that are surrounded by an extracellular matrix composed primarily of collagen IV, laminin and heparan sulfate. Disruption of ganglionic integrity, …
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Selective damage to and protection of enteric neurons in vitro in models of ischemia and reperfusion
… animal models of IBD have demonstrated that intestinal inflammation is typified by the early loss of enteric neurons. It has been proposed that ischemia may occur in intestinal inflammation, due to the organization of splanchnic circulation combined with local inflammatory damage. Therefore, …
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Role Of Actg2 Mutations In Visceral Myopathy
… characterized by dysfunction and weakness of smooth muscle in visceral organs including bowel, bladder, and uterus. When the bowel is primarily affected, the disease is called myopathic chronic intestinal pseudo-obstruction (CIPO). Multi-organ dysfunction involving bowel and bladder is known …
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Left, Right, and Center: A Novel Midline Barrier Separates Asymmetric Extracellular Matrix During Intestinal Development
Correct intestinal morphogenesis depends on the early embryonic process of gut rotation, an evolutionarily-conserved program in which a straight gut tube elongates and forms into its first loops. The gut tube requires guidance to loop reproducibly, however. The dorsal mesentery (DM) connects the …
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Avaliação da atividade espasmolítica das partes aéreas e das raízes de Solanum paniculatum L.: um estudo comparativo.
… roots ( SP - EtOH R ) of Solanum paniculatum in smooth muscle models and elucidate action mechanism of the extract to present the better spasmolytic effect in one of the tested organs . Rat aorta: SP - EtOH PA and SP - EtOH R (243 and 729 μg/mL , n = 3) relaxed organ to pre - contracted with …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
… atropine, 5-HT and its related drugs on intact intestinal segments taken from the ileum of adult and neonate rats. The application of ACh (3nM-1mM) and 5-HT (3nM-1mM) induced contractions in a concentration dependent manner in all tissues examined. The 5-HT induced contractions were only …