Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Intestinal macrophages"”.
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Intestinal macrophages in health and inflammation
The healthy large intestinal mucosa contains a vast pool of macrophages (mφ) that are close to the local bacterial flora and have several unique phenotypic and functional properties compared with other mφ populations. Although human colonic mφ retain some of the hallmark functions of mφ, such as …
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A Molecular Basis for Macrophage Control of Enteric Nervous System Function
… propels food down the length of the gastrointestinal tract to promote nutrient absorption. Interactions between intestinal macrophages and the enteric nervous system regulate gastrointestinal motility, yet we have an incomplete understanding of the molecular mediators of this crosstalk. …
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Mononuclear phagocyte activation and its role in HIV-1 pathogenesis
… response despite the role of monocytes and macrophages as key regulators of inflammatory responses. In this thesis, I focused on the relationships between mononuclear phagocyte activation and HIV-1 pathogenesis, both <i>in vitro</i> using model systems and <i>in vivo</i> in African patients …
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Receptor Mediated Oral Delivery Of Bioencapsulated Green Fluorescent Protein Expressed In Transgenic Chloroplasts
… in vitro GM1 binding assay. GFP was seen in the intestinal mucosa, liver and spleen of mice orally fed with CTB-GFP expressing leaves, while CTB was detected only in the intestinal cells. Intestinal macrophages and dendritic cells stained positive for both the CTB as well as GFP. These results …
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Investigating the role of IgG and Fcγ receptors in intestinal inflammation
… mechanism by which local IgG might contribute to intestinal inflammation. We found that UC and murine dextran sodium sulfate (DSS)-induced colitis are associated with a significant increase in anti-commensal IgG and local enrichment of FcγR signalling pathway genes. The genes most robustly …
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Interactions Between Microbial, Neuronal, and Immune Cells in the Digestive System
… system (ENS). In concert with the commensal intestinal microbiota, the enteric immune and nervous systems communicate with one another, and this crosstalk was the focus of my thesis work. The studies as presented here are divided into two parts: The first part will focus on the influence of …