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Showing 1 to 8 of 8 for “"Intestinal Smooth Muscle Cells"”.
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Epigenetic Modification of Phenotype in Intestinal Smooth Muscle Cells
Inflammation causes proliferation of intestinal smooth muscle cells (ISMC), contributing to the thickened intestinal wall and the dysmotility symptoms observed in inflammatory bowel disease (IBD). A unique consequence of Crohn’s disease (CD), a subset of IBD characterized by chronic, transmural …
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Electrical Properties and the Sodium, Potassium, and Chloride Content of Intestinal Smooth Muscle Cells
Made available in DSpace on 2014-12-05T22:14:39Z (GMT). No. of bitstreams: 1 5900469.pdf: 4006299 bytes, checksum: 5200802e70074f1d4c614d25da06996e (MD5) Previous issue date: 1958
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Inflammation Promotes the Processing of Glial Cell-Line Derived Neurotrophic Factor by Matrix Metalloproteinase-9 in Intestinal Smooth Muscle Cells
The control and regulation of all major intestinal functions are coordinated by neurons within the enteric nervous system (ENS). While intestinal inflammation initially causes a profound loss of enteric neurons, the ENS demonstrates remarkable changes in neuronal structure and function to retain …
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Differentiation and contractility of colon smooth muscle under normal and diabetic conditions
Intestinal smooth muscle development involves complex transcriptional regulation leading to cell differentiation of the circular, longitudinal and muscularis mucosae layers. Differentiated intestinal smooth muscle cells express high levels of smooth muscle-specific contractile and regulatory …
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Selective damage to and protection of enteric neurons in vitro in models of ischemia and reperfusion
… animal models of IBD have demonstrated that intestinal inflammation is typified by the early loss of enteric neurons. It has been proposed that ischemia may occur in intestinal inflammation, due to the organization of splanchnic circulation combined with local inflammatory damage. Therefore, …
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Role Of Actg2 Mutations In Visceral Myopathy
… characterized by dysfunction and weakness of smooth muscle in visceral organs including bowel, bladder, and uterus. When the bowel is primarily affected, the disease is called myopathic chronic intestinal pseudo-obstruction (CIPO). Multi-organ dysfunction involving bowel and bladder is known …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
… atropine, 5-HT and its related drugs on intact intestinal segments taken from the ileum of adult and neonate rats. The application of ACh (3nM-1mM) and 5-HT (3nM-1mM) induced contractions in a concentration dependent manner in all tissues examined. The 5-HT induced contractions were only …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
… atropine, 5-HT and its related drugs on intact intestinal segments taken from the ileum of adult and neonate rats. The application of ACh (3nM-1mM) and 5-HT (3nM-1mM) induced contractions in a concentration dependent manner in all tissues examined. The 5-HT induced contractions were only …