Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Intersectional genetics"”.
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Dissecting the Functional Heterogeneity of Serotonergic Systems That Regulate Fear and Panic
… of amygdala-projecting DRD/DRV cell bodies using intersectional genetics reduced extinction of conditioned fear behavior and enhanced anxiety avoidance. In Chapter IV, retrograde tracing showed that the PeFR was innervated by equally selective serotonergic networks concentrated in the lateral …
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Molecular and Genetic Analysis of Neuropeptide Signalling in Mammalian Circadian Timekeeping
… The first two experimental chapters utilise intersectional genetics and viral transduction to address separable roles for the VIP and VPAC2 cell populations. By diphtheria toxin-mediated cell ablation, or by adjusting cell-autonomous periodicity or rhythmicity specifically in these cell …
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Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System
… loss in iEAN numbers and chronic dysmotility. Intersectional genetics, pharmacological intervention, and chemogenetic sympathetic activation was used to demonstrate that MM-specific Β2AR signaling is required to confer neuronal protection during the course of infection and prevent further …
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Exploring the role of Gastrin-Releasing Peptide Neurons in Circadian Time-Keeping of the Suprachiasmatic Nucleus
… GRP. Finally, I present validation of two new intersectional mouse lines in which Grpr-Flp and Vip-Flp can be combined with the Grp-Cre allele. By using suitable Cre- and Flp-dependent AAV-expressed reporters and effectors, these will facilitate future analyses of the complete Grp-Grpr axis and …