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Showing 1 to 2 of 2 for “"Internalizing receptor"”.
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Identification of the receptor for cellular internalization of an anti-nucleic acid antibody, 3D8 scFv
… fragment (scFv) Ab, has been known to be an internalizing antibody that enters the cells by caveolae/lipid-raft-mediated endocytosis. However, cell surface receptor for 3D8 scFv internalization remains unknown. Here, we studied for cell surface receptor of 3D8 scFv for cellular …
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Arming adoptively transferred T-cells with drug-loaded nanoparticles for cancer immunotherapy
… On the other hand, we identified CD45 as a non-internalizing receptor on T-cells that could be used as an anchor to block internalization of cell surface-conjugated nanoparticles. Anti-CD45 decorated nanogels consisting of IL-15 superagonists remained on T-cells surfaces for over 12 days and …