Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 121 for “"Interleukin-6 (IL-6)"”.
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Autocrine Effects of Catecholamines on Macrophage Release of Interleukin-6 (IL-6)
… have both stimulatory and inhibitory effects on interleukin-6 (IL-6). This study was designed to clarify the autocrine role of macrophage-derived NE on IL-6 production in activated peritoneal macrophages. Effects of NE on IL-6 production in the RAW264.7 macrophage cell-line also were …
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Spatially-defined quantitative interleukin 6 (IL-6) detection using polyethylene glycol microgel sensors (μGELISA)
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Effects of N-3 polyunsaturated fatty acids on adipose stem cell production of interleukin-6 (IL-6)
Thesis (M.S.)--Michigan State University. Human Nutrition, 2010
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Respiratory muscle work and inspiratory muscle training on cytokines, oxidative stress and diaphragm fatigue in younger and older populations
… respiratory muscle work also elevates cytokines interleukin-6 (IL-6) and interleukin-1β (IL-1β) within the respiratory muscles and systemically. There is mounting evidence that inflammation contributes significantly to the ageing process and age related diseases. Enhanced oxidative stress, …
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Cytokine and neurotransmitter regulation of glial cell production of Il-6; indications for neurodegenerative disorders
The cytokines interleukin-1 (IL-1) and interleukin-6 (IL-6) are produced during an immune reaction and cause inflammation and swelling of the surrounding tissue. AD is a neurodegenerative disorder characterized by well-defined neuropathologic entities. Both IL-1 and IL-6 are present in senile …
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Überlebenszeitabhängige Änderungen der zerebralen IL-6- und GFAP-Expression nach letalen Schädel-Hirn-Traumen
… Auszählung des zellulär sezernierten Zytokins Interleukin-6 (IL-6) und des zerebralen Intermediärfilamentes Saures Gliafaserprotein (GFAP) hinsichtlich ihrer Aussagekraft zur Detektion eines Schädel-Hirn-Traumas (SHT) und der Abschätzung des Überlebenszeitintervalls zwischen Erleiden der …
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Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro
… Transforming Growth Factor-beta-1(TGF-beta-1), Interleukin-6 (IL-6), Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und Cortisol (bzw. Dexamethason) auf das humane Myokard. Um Rückschlüsse auf mögliche Hypertrophie induzierende bzw. Hypertrophie inhibierende Effekte zu …
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Contribution of Interleukin 6 Trans Signaling In Pulmonary Fibrosis
… is unknown, there are no effective treatments available. Inhibition of interleukin 6 (IL-6) results in the attenuation of pulmonary fibrosis in mice. It is unclear whether this is due to blockade of classical<em> </em>signaling, mediated by membrane-bound IL-6 receptor alpha (mIL-6Rα), or trans …
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Detection of glial interleukin-6 release: Development of a novel interleukin-6 Elisa
The development of an interleukin-6 (IL-6) enzyme-linked immunosorbent (ELISA) assay resulted in a detection range of 1 ng/m1 to 10 ng/mL IL-6. The limit of detection (LOD) for IL-6 was 0.25 ng/mL. Troubleshooting techniques were attempted including matrix effects, non-specific binding, and coating …
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Interleukin-6, Depression, and Religious Coping in Older Seventh-day Adventists
… depressive symptoms and the inflammatory marker, interleukin-6 (IL-6), interact over time in 287 older adults (54% female, 63% White, Mage = 66, SDage = 10.9) from the Biopsychosocial Religion and Health Study and whether religious coping moderated this relationship. Depressive symptoms and IL-6 …
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Adenylyl Cyclase 2 Selectively Regulates IL-6 Expression in Human Bronchial Smooth Muscle Cells
… overexpression and activation of AC2 enhanced interleukin 6 (IL-6) expression, but overexpression of AC3 or AC6 had no effect. IL-6 production by BSMC was induced by Fsk and select G protein-coupled receptor (GPCR) agonists, though IL-6 levels did not directly correlate with intracellular cAMP …
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Kontinuierliche Überexpression von Interleukin-6 im Zentralnervensystem : lokale Applikation d. Designerzytokins Hyper-Interleukin-6 im adulten Organismus d. Ratte u. Auswirkungen v. exzitatorischen Neurotoxinen im Interleukin-6 transgenen Mausmodell
Im ersten Teil der vorliegenden Arbeit wurde ein Modell zur langfristigen, kontinuierlichen Expression des Designerzytokins Hyper-Interleukin-6 (H-IL-6) im <br>Zentralnervensystem (ZNS) entwickelt. H-IL-6 besteht aus humanem Interleukin-6 (IL-6) verbunden mit löslichem IL-6 Rezeptor (sIL-6R). …
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Epidermal growth factor-mediated activation of the unliganded glucocorticoid receptor in A549 cells
… examples of EGF repressing the expression of interleukin 6 (IL-6) mRNA occur in other cell types and whether the effects of EGF are mediated via the GR. This study provides the first evidence of a single ligand (EGF) causing ligand-independent GR activation, resulting in the regulation of …
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Borrelienneuropathie - eine histologische und immunhistochemische Charakterisierung
… Zytokine Tumor Nekrose-Faktor-alpha (TNF-alpha), Interleukin-1ß (IL-1ß) und Interleukin-6 (IL-6), als auch Metalloproteinase MMP-9 durchgeführt, ferner mit Antikörpern gegen das membranassoziierte Glykoprotein HLA-DR3. Zusätzlich wurden Semi-Dünn-Schnitte angefertigt. Klinisch wiesen die meisten …
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Surface functionalisation of encoded SU-8 microparticles and their uses in multiplexed suspension biological assays
… diffractive elements and can encode millions of unique codes. In this thesis, the preparation and surface modification of different diffractive microparticles; the attachment of a range of biological molecules (e.g. proteins and peptides) onto the functionalised surfaces; and different …
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Progesterone Receptor Regulation of the Gene Networks That Control Ovulation in Mice
… hormone (LH) induces ovulation, releasing a fertilizable egg from a mature ovarian follicle. Although ovulation is a physiologically well-characterized event, the underlying molecular processes remain poorly understood. Based on research performed over the past twenty years, the steroid hormone …
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Value of Raisins for Reduction of Oxidative Stress, Endothelial Dysfunction, and Inflammation in Obesity
This study investigated the effects of daily consumption of Thompson seedless raisins on markers of inflammation, oxidative stress and endothelial activation in response to an acute high-fat meal in obese individuals. Seventeen overweight men and women consumed raisins or placebo (264 kcal/d) for …
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Characterization of an in vitro exercise model and the effects of a metabolic endotoxemia on skeletal muscle adaptation to electric pulse stimulation
… myotubes for varied lengths of time and measured interleukin-6 (Il-6), peroxisome proliferator-activated receptor gamma coactivator 1- (PGC1-), superoxide dismutase 2 (SOD2), substrate metabolism, metabolic enzyme activity, heat stress markers, and pH. To recreate the inflammatory milieu observed …
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The Role of Interleukin-6 in the Regulation of Glucose Sensing in Hypothalamic GT1-7 Neurons
… an increase in inflammatory mediators including interleukin-6 (IL-6). The aim of the current study was to investigate whether IL-6 played a role in the regulation of central glucose sensing. This was addressed by examining the effects of IL-6 exposure on electrophysiological and biochemical …
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Evaluation of Endothelial Cell Responses to Elevated Glucose
… design of new vascular devices specifically tailored to diabetic patients. In contribution toward this model, this thesis assessed Human Umbilical Vein Endothelial Cell (HUVEC) responses to high glucose conditions. Interleukin 6 (IL-6) and Cluster of Differentiation 36 (CD36) were selected to …
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