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Showing 1 to 11 of 11 for “"Interleukin-18"”.
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Einfluss von Interleukin-18 auf das Th1/Th2-Zytokingleichgewicht mononukleärer Nabelschnurblutzellen in vitro
IL-18 wurde erstmals 1989 beschrieben und lange Zeit als "IFN-Gamma inducing factor" bezeichnet, welcher die Ausbildung einer Th1-Immunantwort stimuliert. In den letzten Jahren konnte für IL-18 zudem die Induktion Th2-spezifischer Zytokine aufgezeigt werden. Bei Atopikern, welche durch das …
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Klonierung und Charakterisierung des Zytokins Interleukin-18 sowie der Zelloberflächenproteine CD3 epsilon, CD4, CD8 alpha und MHCII beta der Ente : Generierung von Werkzeugen für immunologische Studien im Enten-Hepatitits-B-Virus-Modell
… behindert. <br>Das Zytokin IL-18 kann je nach der An- oder Abwesenheit anderer Zytokine eine Immunreaktion des Typs Th1- aber auch des Typs Th2 hervorrufen. Im HBV-transgenen Mausmodell inhibiert IL-18 die hepadnavirale Replikation in der Leber. <br>Daher sollte das IL-18 der …
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Equine interferon-gamma and associated cytokines
… medied immune responses. In a broader sense, interleukin-12 and interleukin-18 can also be classified as type I cytokines in as much as they are able to shift the CD4+ cytokine expression pattern to a Thl phenotype and specifically stimulate IFN-γ production not only by T helper cells, but …
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Short- and Long-Term Effects of Commercially Available Gold Nanoparticles in Rodents
… serum levels of the proinflammatory cytokine interleukin-18. No such alterations were found in rats. Species differences in GNP biodistribution and excretion were also detected, with higher relative accumulation of GNPs in spleen and longer fecal excretion in rats. In the long-term (20 weeks …
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Alpha-Fetoprotein-spezifische Immuntherapie des hepatozellulären Karzinoms mittels DNA-Immunisierung
… Effekte der mAFP/Zytokin-Koimmunisierung mit Interleukin-12 (IL-12), Interleukin-18 (IL-18) u. Granulozyten-Makrophagen-Kolonien-stimulierendem Faktor (GM-CSF) untersucht. Dabei wurde die DNA sowohl mittels „Gene Gun“ als auch i.m. appliziert. So konnte die immunologische Ignoranz gegenüber …
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The Relationship of Inflammatory Markers to Cognitive Function in a Population-Based Sample
C-reactive protein (CRP), Interleukin-18 (IL-18), Monocyte chemoattractant protein (MCP-1), and Lipoprotein-associated phospholipase (Lp-PLA2) are pro-inflammatory blood markers that appear to play critical roles in atherosclerosis and vascular disease, and have been linked to Alzheimer’s Disease, …
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Significant Association of IL-18 Genetic Polymorphisms with Aspirin-Intolerant Urticaria in a Korean Population
… infiltration have been suggested to be involved. Interleukin-18 (IL-18) can stimulate mast cells and then release inflammatory mediators such as IL-4, IL-13 by stimulating mast cells. IL-18 activates neutrophils by inducing the production of TNFα, which in turn induces the synthesis of leukotriene …
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TLR4 endogenous ligand S100A8/A9 levels in adult-onset Still’s disease and their association with disease activity and clinical manifestations
… of S100A8/A9, follistatin-like protein 1 and interleukin-18 (IL-18). Of the AOSD patients, follow-up samples were collected from 16 patients after resolution of disease activity. Furthermore, S100A8/A9 expression levels in biopsy specimens obtained from 26 AOSD patients with skin rashes and 8 …
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The nature of cachexia in patients with heart failure and stable coronary artery disease
… levels of tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), leptin, adiponectin, and Btype natriuretic peptide (BNP) were measured. Skeletal muscle biopsies were analysed for the expression of messenger ribonucleic acid (mRNA) for TNF-α, IL-6, interleukin-1β …