Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Interleukin-17A"”.
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Vergleichende Untersuchungen zum Effekt von Interleukin-17A auf den Meniskus und hyalinen Gelenkknorpel im Rindermodell
… Arbeit war die Untersuchung des Einflusses von Interleukin-17A auf das Meniskusgewebe – teils vergleichend zum Gelenkknorpel - und die Kombination des Zytokins mit einer mechanischen Verletzung im Rahmen eines in-vitro-posttraumatischen Milieus. Gewebeexplantate in einer Höhe von ca. 1 mm und 3 …
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Identifying a Target Protein and Ligands for Autoimmune Disorders
… factor for pro-inflammatory cytokine interleukin-17A (IL-17A), which is highly involved in inflammatory reactions within the body. To search for a treatment for SLE, computer aided drug discovery techniques were utilized. The transcription factor complex for IL-17A was reconstructed …
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ESTROGEN, VASCULAR INFLAMMATION, AND INTERLEUKIN-17 IN RELATION TO ATHEROSCLEROSIS IN A FEMALE NONHUMAN PRIMATE MODEL
The role of T helper 17 (Th17) cells and interleukin-17A (IL-17A), a signature pro-inflammatory cytokine for Th17, in atherosclerosis is unknown. Postmenopausal estrogen therapy (ET) mediates atheroprotection in part through anti-inflammatory effects; however, the effects of ET on Th17 cells and …
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Preclinical evaluation of a vaccine against IL-17 mediated inflammatory diseases including psoriasis
Psoriasis is a chronic autoimmune skin condition. Interleukin 17A (IL-17A) is a pro-inflammatory cytokine with a key role in the pathogenesis of this disease. Antibodies targeting IL-17A have shown superior efficacy compared with other psoriasis treatments, and long-term studies have demonstrated …
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Defining the role of the transcription factor T-bet in the innate immune system in intestinal inflammation.
… that chronic IBD in TRUC mice was dependent on interleukin-17A (IL-17A) producing IL-7R+ CD90+ innate lymphoid cells (ILCs). Depletion of ILCs or IL-17A neutralization cured disease. Cytokines responsible for driving innate IL-17A included IL-23, IL-6 and TL1A. IL-23 and IL-6 played functionally …
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The Role of IL-6 in Inflammatory Aortic Aneurysmal Diseases
Interleukin-6 (IL-6), a member of a superfamily of cardioactive cytokines, has been identified as an independent biomarker of vascular diseases including atherosclerosis and aortic aneurysms. Local vascular IL-6 secretion can be induced by dysregulated angiotensin II (Ang II) signaling, producing …
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ESPRESSIONE DELL'IL-17A NELLA DINAMICA PATOGENETICA DELLA POLIPOSI NASALE
… STATI EFFETTUATI NUMEROSI STUDI; SEMBRA CHE L'IL-17A SVOLGA UN RUOLO IMPORTANTE NELLA PATOGENESI DELLA POLIPOSI NASALE.
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Roles of γδ T Cells in Influenza Infections and Methods for TCR Expression and Characterization
… influenza infection induced the accumulation of interleukin-17A (IL-17A)-producing γδ T cells, which was associated with IL-33 production by lung epithelial cells. Neonates lacking IL-17A-expressing γδ T cells or Il33 had higher mortality upon influenza infection. γδ T cells and IL-33 promoted …