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Showing 1 to 4 of 4 for “"Interferon stimulated gene 15"”.
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A Role for Interferon Stimulated Gene-15 (ISG15) During Chikungunya Virus Infection
<p>Abstract of the Dissertation</p><p>A Role for Interferon Stimulated Gene-15: ISG15) During Chikungunya Virus Infection</p><p>By</p><p>Scott William Werneke</p><p>Doctor of Philosophy in Biology and Biomedical Science</p><p>(Immunology)</p><p>Washington University in St. Louis, …
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Biophysical Characterization of the vOTU Proteases from the CCHF and Dugbe Nairoviruses
… via Ubiquitin (Ub) as well as the Ub-like interferon-stimulated gene 15 (ISG15). vOTU homologs have been found in numerous viruses across several families. Moreover, the effects of these viruses range in severity from mild flu-like symptoms to mortality depending on the species of the …
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An Imaging Approach to Examine Telomere Dynamics and Regulation of Gene Expression with Aging
… age has been associated with shifts in gene expression through models such as the telomere position effect (TPE), which suggests reduced interference of the telomere with transcriptional activity of increasingly more distant genes. A modification of the TPE model, referred to as Telomere …
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Species Preference of Viral Deubiquitinating Proteases Toward ISG15 Through Structural and Enzymatic Characterization
… editing of host Ub and Ub-like molecules such as interferon stimulated gene 15 (ISG15), have been identified as a potential virulence factor through their role in evading the innate immune response. Study and characterization of vOTUs involves evaluating their activity and preferences for Ub, …