Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Interferon regulatory factor 1"”.
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Chemical genetic manipulation of interferon regulatory factor 1 (IRF-1) using synthetic biology
Interferon regulatory factor 1 (IRF-1), the founding member of IRF family, is a nuclear transcription factor first described as a transcription factor that binds to the upstream region of interferon induced genes following viral infection. In addition, IRF-1 has been reported to be involved in cell …
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The regulation of human airway epithelial expression of viperin by human rhinovirus
… and is dependent on induction and DNA binding of interferon regulatory factor 1 (IRF-1). We showed that CSE inhibits HRV-induced viperin mRNA and protein expression but that CSE does not alter HRV-induced promoter activation, raising the possibility that CSE-mediated inhibition of viperin …
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Anti-Inflammatory Mechanism By Oxysterols In Cultured Rat Brain Astrocytes
… I treated lipopolysaccharides(LPS)- or interferon gamma(IFN-stimulated rat brain astrocytes with two oxysterols, 7-ketocholesterol and 22(R)-hydroxycholesterol. In LPS-stimulated astrocytes, both oxysterols suppressed inducible nitric oxide synthase expression and nitric oxide release …
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Characterization of the antiviral activity of cyclosporine A against dengue virus
… cyclophilin A or B, which are not required host factors for DENV-2 in Huh7 and A549 cells. In Huh7 and A549 cells, CsA induces interferon regulatory factor-1 (IRF1)-dependent antiviral gene expression. While CsA does not increase IRF1 levels in Huh7 cells, it enhances IRF1 protein levels in A549 …
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New Roles for Mitochondria in Shaping Antiviral and Stress Responses
… responses including apoptosis and type I interferon signaling (IFN-I). While apoptosis and IFN-I mediated by Mitochondrial AntiViral Signaling (MAVS) are well-established defenses, new dimensions of mitochondrial biology are emerging as battlefronts during viral infection. Increasingly, it …
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Interference of Toxoplasma gondii with IFN-γ-regulated gene expression of its host cell
… nur lebende Parasiten die Expression des interferon regulatory factor-1 (IRF-1). Des weiteren verringern beide, lebende T. gondii und Parasitenlysat, die transkriptionelle Aktivität des CIITA Promotor IV, während nur lebende T. gondii dazu fähig sind einen minimalen GAS enthaltenden …