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Showing 1 to 2 of 2 for “"Inter-alpha-inhibitor"”.

  1. Role of Covalent Modification of Hyaluronan with Inter-Alpha Inhibitor Heavy Chains During Acute Lung Injury

    … by the heavy chains (HC) of the serum protein inter-alpha-inhibitor (IαI) during inflammation. Known as the only covalent modification of HA, the HC linking of HA is exclusively mediated by the inflammation-induced secreted enzyme TNFα-stimulated gene-6 (TSG-6). Mice deficient for HC-HA …

    iupui Repository record for Role of Covalent Modification of Hyaluronan with Inter-Alpha Inhibitor Heavy Chains During Acute Lung Injury (opens in a new tab)

  2. The Role of Tumor Necrosis Factor-Stimulated Gene 6 Protein (TSG-6) in Osteoarthritis

    … up a model system based on specific regions of interest within a joint corresponding to a gradient of disease severities; this system can be used to represent early (relative intact), intermediate (mild to moderate damaged) and late (severe damaged) disease within the knee joints. We performed …

    duke Repository record for The Role of Tumor Necrosis Factor-Stimulated Gene 6 Protein (TSG-6) in Osteoarthritis (opens in a new tab)