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Showing 1 to 5 of 5 for “"Intensity Modulated Proton Therapy"”.
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Intensity Modulated Proton Therapy Optimization Under Uncertainty: Field Misalignment and Internal Organ Motion
Intensity modulated proton therapy (IMPT) is one of the most advanced forms of radiation therapy, which can deliver a highly conformal dose to the tumor while sparing the dose in healthy tissues. Compared to conventional photon-based radiation therapy, IMPT is more flexible in delivering radiation …
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Evaluation of Radiobiological Effects in Intensity Modulated Proton Therapy : New Strategies for Inverse Treatment Planning
Currently, treatment planning for intensity modulated proton therapy (IMPT) usually disregards variations of the relative biological effectiveness (RBE). To investigate the potential clinical relevance of a variable RBE for beam scanning techniques, new strategies for the evaluation of …
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Improvements In Robustness and Optimality of Intensity-Modulated Proton Therapy Plans For Lung Cancer Patients With 4-Dimensional Robust Optimization
<p>A major challenge in the application of intensity-modulated proton therapy (IMPT) for lung cancer patients is the mitigation and consideration of uncertainties associated with breathing motion in treatment planning. The primary objective of this research was to develop a novel four-dimensional …
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Moment Constraints in Radiation Therapy Planning Optimization Incorporating Patient-Specific Anatomical Geometry
Intensity-modulated proton therapy (IMPT) is an advanced cancer treatment technique, aimed at maximizing tumor control while minimizing collateral damage to surrounding healthy structures. In inverse planning, dose-volume histogram (DVH) is a key concept for measuring and restricting collateral …
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Robust Treatment Planning and Robustness Evaluation for Proton Therapy of Head and Neck Cancer
Intensity modulated proton therapy (IMPT) in head and neck squamous cell carcinoma (HNSCC) offers superior advantages over conventional photon therapy, by generating high conformal doses to the target volume and improved sparing of the organ at risks (OARs). Besides, robust treatment planning …