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Showing 1 to 1 of 1 for “"Integrationsstellenanalyse"”.
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Insights into the clonal inventory of gene corrected human SCID-XI hematopoiesis
The semi-random nature of retroviral integration introduces a stable molecular marker into the cellular genome in the form of a genomic-proviral fusion sequence which can be passed on unmodified to all the progenies of a transduced cell. Retroviral integration site analysis provides a powerful …