Global ETD Search
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Showing 1 to 2 of 2 for “"Insulin secretion pathway"”.
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The Art of Modeling and Simulation of Multiscale Biochemical Systems
… modeling methods to study the behavior of the insulin secretion pathway. We first expand the single cell model proposed by Bertram et. al. to model multiple cells. Synchronization among multiple cells is observed. Then an unhealthy cell model is proposed to study the insulin secretion failure …
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Genetic and non-genetic determinants of drug response in type 2 diabetes
… addition,downstream rare variant burden test and pathway analyses were performed. </p><p class="MsoNormal" style="text-align:justify;line-height:150%"><b>Results</b>: We showed robust association of metformin use with fasting glucagon likepeptide-1 (GLP-1) levels in diabetic and non-diabetic …