Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Insertion sequences"”.
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Mobilome and antibiotic resistance in Acinetobacter baumannii
… The aim of this work was to analyse the role of insertion sequences (ISs), transposon-like structures, resistance-plasmids and ISCR1-like elements in the resistance to carbapenems and ceftazidime in A. baumannii. Fifteen carbapanem-resistant strains of Acinetobacter baumannii isolated from Chile …
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Diversity of acinetobacter baumannii isolates from Egypt
… resistance were found in the collection studied. Insertion sequences ISAba1, ISAba2 and ISAba3 have been found to upregulate the expression of blaOXA genes. ISAba1 was found upstream of blaOXA23 in 18 strains in this collection The first report of ISAba2 was identified upstream of a blaOXA-51-like …
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Engineering structural variants with prime editing
… and scalable manipulation of genomic sequences. Prime editing has emerged as a powerful tool to introduce virtually any type of edit with high precision, but editing efficiency varies between edit types. While first insights into determinants have been gained for small edits, …
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Efficient Algorithms for Prokaryotic Whole Genome Assembly and Finishing
… assemblers in general assemble long contiguous sequences (contigs) using both overlapping reads and linked reads until the assembly runs into an ambiguous repeat region. These contigs are further bridged into scaffolds using linked read information. However, errors can be made in both phases of …
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Molecular and phylogenetic analysis of a Bacillus thuringiensis genetic locus
… $\textit{am1}$ gene was investigated. Two novel insertion sequences (Tl) and (T2) were identified with sequence similarity to IS$\textit{240A}$ from Bti and an insertion sequence associated with the $\textit{Orf1}$ gene of 84-I. The identification of a further incomplete reading frame with …
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Omics-driven and constraint-based modelling of microbial community metabolism
… I also found evidence for the enrichment of insertion sequences in auxotrophic genomes, suggesting a possible mechanism for regulation or gene loss. In the second case study, I teamed up with industrial collaborators to analyse microbial interactions that shape cheese flavour formation. …
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Proteome, transcriptome and metabolome plasticity in closely related strains of Escherichia coli - K12 and its diversity during molecular evolution processes
… E. coli's genetics and several completed genome sequences are available. Among them, the genome sequences of two closely related K-12 non-pathogenic strains, MG1655 and W3110 have been accurately determined. Resequencing of PCR products of selected regions indicates that there is only eight true …
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Epidemiologische und molekulare Untersuchungen zur Biofilmbildung in Staphylococcus epidermidis und Staphylococcus aureus
… bestimmten Umweltfaktoren und dem Einfluß von Insertionssequenzen ab. In einer epidemiologische Untersuchung wurde gezeigt, daß in S. epidermidis das ica-Operon häufiger in klinischen als in kommensalen Stämmen vorkommt. Der überwiegende Teil dieser ica-positiven Stämme bildete phänotypisch …