Global ETD Search
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Showing 1 to 3 of 3 for “"Inscuteable"”.
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ANALYZING THE FUNCTIONS OF PREFOLDIN COMPLEX IN NEUROBLAST HOMEOSTASIS OF DROSOPHILA MELANOGASTER
… brains. Co-depletion of Prefoldin and Partner of Inscuteable (Pins) leads to the formation of gigantic brains with dramatic neuroblast overgrowth, due to the severe asymmetric division defects of both neuroblasts and Intermediate Neural Progenitors (INPs). Co-depletion of Prefoldin and Pins also …
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HEM-protein regulates cell migration and asymmetric cell division during development of the ventral nerve cord in Drosophila melanogaster
… In HemJ4-48 mutants, the apical localization of Inscuteable (Insc) is disrupted, suggesting that regulation of the asymmetric division of GMC-1 by Hem is mediated by Insc. The same symmetric division of GMC-1s was also observed in Abl mutants but not WAVE mutants, suggesting that Abl may act …
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Regulation of Asymmetric Cell Divisions in the Developing Epidermis
… of division. First is the expression of the mInscuteable gene, which is sufficient to drive ACDs. However, there is robust control of division orientation as excessive ACDs are prevented by a change in the localization of NuMA, an effector of spindle orientation. Finally, I show that p63, a …