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Showing 1 to 9 of 9 for “"InsP6"”.
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STRUCTURE-FUNCTION STUDIES OF MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASES FROM GUT COMMENSAL BACTERIA
Inositol hexakisphosphate (InsP6) is the main storage form of phosphorous in animal feeds. Phytases are enzymes (myo-inositol hexakisphosphate phosphohydrolases) that break down InsP6 by hydrolysis to release inorganic phosphate. Non-ruminant animals do not produce phytases needed to digest dietary …
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Structure and substrate specificity of myo-inositol phosphatases at atomic resolution
… myo-inositol- 1,2,3,4,5,6-hexakisphosphate (InsP6) to produce less-phosphorylated myo-inositol phosphates (IPs) containing between one and five phosphoryl groups. To understand PTPLP substrate specificity, I present multiple complex structures of Phytase A from Selenomonas ruminantium …
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Structure and function of PhyA from Desulfovibrio magneticus and use of its product in affinity pull-down experiments
… been determined in the presence and absence of InsP6 substrate in order to identify the structural features that give rise to its 3-4-5 substrate specificity. These include a novel Phy loop conformation and R242 of the HCRGG.GR P-loop signature sequence. Further, PTPLPs containing an arginine …
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Requirement of phosphoinositol-derived signals in the wounding response of Arabidopsis thaliana
… TIR1, der ein Inositol-Hexakisphosphat (InsP6) als Kofaktor enthält, verglichen. Aufgrund der strukturellen Ähnlichkeit zwischen COI1 und TIR1 wurde die Hypothese getestet, dass ein Inositolpolyphosphat-Kofaktor für die COI1-Funktion benötigt wird. COI1-Varianten, in denen putative …
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Connections Between Inositol Phosphate Signaling and Energy Responses in Plants
… myo-inositol (1,2,3,4,5,6)-hexakisphosphate (InsP6), which can serve as a signaling molecule or as storage compound of inositol, phosphorus, and minerals. Even though plants produce huge amounts of InsP6 in seeds, almost no attention has been paid to whether PPx-InsPs exist in plants, and if …
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Expanding our knowledge of protein tyrosine phosphatase-like phytases : mechanism, substrate specificity and pathways of myo-inositol hexakisphosphate dephosphorylation
… pathways of sequential dephosphorylation of InsP6 characterized to date. Bioinformatic analyses have indicated homologues that are involved in the regulation of cellular function.
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ROLES OF INOSITOL DIPHOSPHATES IN DNA REPAIR AND EFFECTS OF ASPIRIN ANALOGUES ON OESOPHAGEAL CANCER
… but also 1-InsP7 and InsP8 to a single product, InsP6. The HPLC data found InsP7 accumulation to be relatively little during InsP8 breakdown by DIPPs. Such low build-up was found to be due to rapid conversion of InsP7 to InsP6. Through this study it is also clear that InsP8 prefers to …
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Biochemical Characterization of Arabidopsis Enzymes Involved in Inositol Pyrophosphate Biosynthesis
… triphosphate 5/6kinase enzymes, that can convert InsP6 to InsP7. Together, these enzymes can function in plants to produce inositol pyrophosphates, which have been implicated in signal transduction and phosphate sensing pathways. The significance and potential application of these findings in …
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Elucidating the function of inositol pyrophosphate signaling pathways in Arabidopsis thaliana
… myo-inositol. Inositol hexakisphosphate (InsP6) is the most abundant InsP signaling molecule and can be phosphorylated by the multifunctional inositol tetrakisphosphate 1-kinase 1 (ITPK1) and diphosphoinositol pentakisphosphate (VIP) kinases, resulting in inositol pyrophosphates …