Global ETD Search
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Showing 1 to 2 of 2 for “"Inositiol trisphosphate receptor"”.
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High-resolution optical analyses of IP3-evoked Ca2+ signals
… responses. Most cells express inositol 1,4,5-trisphosphate receptors (IP3R) that mediate Ca2+ release from the endoplasmic reticulum (ER) when they bind IP3 produced after activation of cell-surface receptors. Vertebrate genomes encode three closely related subtypes of IP3R (IP3R1-3). …
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Ca2+ signalling between the endoplasmic reticulum and lysosomes
… Stimulation of the endogenous muscarinic (M3) receptors of human embryonic kidney (HEK) cells with carbachol results in the activation of phospholipase C (PLC) and formation of inositol 1,4,5-trisphosphate (IP3), activation of IP3 receptors (IP3Rs), release of Ca2+ from the endoplasmic …