Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Innate lymphoid cell"”.
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Innate Lymphoid Cell Diversity in Pregnancy and Ovarian Cancer
… of immune suppression and reduced cytotoxicity. Innate Lymphoid Cells (ILCs) are a diverse group of lymphocytes which exhibit tissue specific phenotypes and functions. They are found in both the uterine lining during early pregnancy (decidua) and the ascites of ovarian cancer patients. Despite …
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Innate Lymphoid Cell Characterization and Ilc2S In Neuroinflammation In Aging and Sex Differences
… are mounted, males are better at CD4+ T cell type (Th1) responses, while females prefer Th2 responses. As tissue-resident innate lymphoid cells (ILC) are novel immune cells that are the innate complement to T cells, understanding their role in aging and sex differences is imperative.</p> …
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Investigating lymphocyte development in the foetal thymus and modulation by the melanocortin 5 receptor
… the generation of effective protective immunity. Innate lymphoid cells and T cells play central roles in orchestrating bespoke immune reactions by producing specialised repertoires of immuno-regulatory cytokines. ILC2 and natural killer (NK) cells are generated in the bone marrow and thymus, …
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IL-25 and B cells in atherosclerosis
… In the present work we report that different B cell subsets could potentially be used as biomarkers for the prediction of future stroke events. Specifically, our findings demonstrate an association between high levels of CD19+CD40+ cells and a decreased risk of stroke while high levels of …
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Identifying regulators of natural killer cell development through CRISPR screening of common lymphoid progenitors
Natural Killer (NK) cells are cytotoxic lymphocytes that perform a key role in the innate immune response, lysing abnormal host cells such as those that are cancerous or virally infected. They are the prototypic member of the innate lymphoid cell (ILC) family, which also comprises the functionally …
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Imaging innate immune cell behaviour in lymphoid organs
Innate immune cells generate the early host response to infection and tissue injury. Neutrophils are rapidly recruited from circulation to inflammatory tissues for pathogen killing. Type 2 innate lymphoid cells (ILC2s) mediate early responses to helminths and allergens via cytokine production. …
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Innate immunity in defence against infection and tissue repair of the urinary tract
… A complex network of tissue-resident immune cells exists throughout the urinary tract that are vital for initiating and propagating local immune responses, however our understanding of their nature and function remains incomplete. In this thesis, we aim to understand two broad areas of tissue …