Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Innate immune regulation"”.
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Modulation of macrophage metabolism and function by the helminth peptide FhHDM-1
… strategies to regulate their host’s immune response, to prevent expulsion and establish chronic infections. Understanding how they achieve this offers a therapeutic strategy for the treatment of human diseases which are caused by unregulated inflammation. Previous characterisation of …
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Functional characterization of human and chicken TLR3
… receptor 3 (TLR3) is a critical component of the innate immune system, responsible for detecting viral double-stranded RNA (dsRNA) and initiating downstream signaling pathways, including activation of the transcription factor NF-κB. While TLR3 function has been extensively characterized in humans …
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Mechanisms of Innate Immune Dysfunction During Mycobacterium tuberculosis and HIV Co-infection
… during co-infection. Although cell-mediated and innate immunity are known to contribute, the mechanisms leading to exacerbated pulmonary inflammation and increased pathogenesis are largely unknown. The long-term goal of this study is to characterize innate immune signaling responses of …
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Immunomodulatory activity of Lacticaseibacillus rhamnosus R0011: analysis of secretome-mediated impacts on innate immune outcomes in intestinal epithelial cells and antigen presenting cells
… rhamnosus R0011, are associated with immune modulatory activities including down-regulation of pro-inflammatory gene transcription and expression. While host intestinal epithelial cells (IECs) and antigen-presenting cells (APCs) can interact directly with both commensal and pathogenic …