Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 14 of 14 for “"Inla"”.
-
Characterization of virulence-attenuated Listeria monocytogenes common among food and food-associated environments but rarely associated with disease
… stop codon (PMSC) in the key virulence gene, inlA. The virulence factor Internalin A (InlA; encoded by inlA), facilitates the uptake of L. monocytogenes by epithelial cells that express the human isoform of E-cadherin and allows for pathogen traversal across the intestinal barrier in order to …
-
Identification and characterization of the inlGHE gene cluster of Listeria monocytogenes
… into mammalian cells, the combination mutants inlA/GHE, inlB/GHE, inlC/GHE, inlA/B/GHE, inlB/C/GHE, inlA/C and inlA/C/GHE were constructed. Transcription of the genes inlA, inlB and inlC in these mutants was studied by RT-PCR. Deletion of inlGHE enhances transcription of inlA and inlB, but not …
-
Computational Bayesian inference using low discrepancy sequences
The Integrated Nested Laplace Approximation (INLA) provides fast and accurate Bayesian inference for complex hierarchical models. For INLA, and other deterministic methods, the hyperparameter space is explored and points are laid out in a grid structure. These points are used in some numerical …
-
Spatial and Spatiotemporal Modeling of Epidemiological Data
… data. Chapter three describes recently developed INLA as an alternative of traditionally used MCMC in Bayesian hierarchical models. INLA method was used to identify the best regression model for the spatiotemporal regression analysis of Lyme disease count data with climatic covariates in …
-
Modelling the spatial and temporal distribution of Bacillus anthracis suitability across Uganda and Kenya: A Bayesian Approach
… of the Integrated Nested Laplace Approximation (INLA), a spatial method that can be applied to structurally complex data, to model the suitability of B. anthracis. In Chapter 3, I apply a common conventional algorithm to analyse a 15- year dataset comprising confirmed and probable wildlife, …
-
Caracterização fenotípica e molecular de isolados de Listeria monocytogenes obtidos em uma planta de processamento de carne bovina
… pulsado (PFGE), detecção de genes de virulência (inlA, inlB, inlC, inlJ, plcA, hlyA, actA e iap) e testes de resistência a antimicrobianos. Listeria spp foi identificada em 61 (22.4%) das amostras analisadas, L. monocytogenes em 23 (8.5%), L. innocua em 46 (16.9%), e L. seeligeri em 1 (0.37%). Um …
-
Bayesian spatio-temporal modelling, mapping and prediction of disease risk
… μέθοδο Integrated Nested Laplace Approximation (INLA), η οποία είναι κατάλληλη για λανθάνοντα Γκαουσιανά μοντέλα υψηλής διάστασης. Η προτεινόμενη μεθοδολογία εφαρμόζεται σε προσομοιωμένα επιδημιολογικά δεδομένα που αναπαριστούν τη χωρική και χρονική εξέλιξη νόσου στην Κένυα. Στο πλαίσιο της …
-
Identification and Characterization of Interferon-Stimulated Regulators of Bacterial Infection
… c-Met) as well as bacterial surface internalins (InlA and InlB). Additionally, FcγRIa-mediated uptake occurs independently of L. monocytogenes opsonization or canonical FcγRIa signaling. Importantly, I established the contribution of FcγRIa to L. monocytogenes infection in phagocytic cells, thus …
-
Advances in spatial modeling for complex data with applications to symbolic data and spatial transcriptomics.
… the Integrated Nested Laplace Approximation (INLA). A bivariate visualization tool is also developed to aid interpretation of the joint behavior of these features across space. Third, SPHERE (Spatial Poisson Hierarchical modEl with pathway-infoRmed gEne networks) is proposed, a Bayesian …
-
Models and methods for computationally efficient analysis of large spatial and spatio-temporal data
… as the integrated nested Laplace approximation (INLA) approach that is based on a stochastic partial differential equation (SPDE) framework. To model geostatistical data, a latent spatial Gaussian Markov random field (GMRF) with an EAR model prior is applied. The GMRF is defined on a fine grid …
-
Models and Methods for Random Fields in Spatial Statistics with Computational Efficiency from Markov Properties
… with Integrated Nested Laplace Approximations (INLA) and an importance sampling-based algorithm for estimating joint probabilities.
-
Talking stones : the politics of memorialisation in post-conflict Northern Ireland
… and the sectional/oppositional narrative of the INLA/IRSP, respectively. Chapters 8 and 9 examine the projection of Loyalist narratives of the conflict, focusing, respectively, on the UVF and the UDA. Chapter 10 is concerned with the relationship between ‘memory makers’ and ‘memory receivers’ …
-
Interaktion von Listeria monocytogenes mit Endothelzellen
… HUVEC in einer von den Oberflächenproteinen InlA, InlB und ActA unabhängigen Weise von L. monocytogenes invadiert. Wurde das Gen, welches für den positiven Regulationsfaktor PrfA kodiert, deletiert, reduzierte dies die Invasionsrate beträchtlich. Listerienstämme mit einer Deletion im für InlB …
-
Advancements in environmental statistics concerning multiple data sources
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms