Global ETD Search
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Showing 1 to 14 of 14 for “"Inhibition Concentration"”.
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Antimicrobial Nanoparticles: A Green and Novel Approach for Enhancing Bactericidal Efficacy of Commercial Antibiotics
… bacteria. A significant reduction in the minimum inhibition concentration (MIC) of Cef-GNPs was observed as compared to the ceftazidime by itself against Gram-negative bacteria. The MIC of Cef- GNPs were 0.1 mg mL<sup>-1</sup> (P. aeruginosa and E. aerogenes) and 1.2 mg mL<sup>-1</sup> (E. durans …
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Effet de la bradykinine sur la perméabilité des cellules endothéliales d'aorte bovine
… de l'ordre de 57% de la valeur basale à la concentration de 10-8M (p<0,01). De plus, l'effet concentration-dépendant de la BK est biphasique. Cette effet demeure lorsque la BK est administrée avec le MERGETPA, un inhibiteur de la carboxypeptidase M. Cependant, l'agoniste B1 des-Arg9BK, …
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Experimental and modelling studies on the phase behaviour of mutual solvents and their transport through porous media in oil/brine/mutual solvent systems in the context of scale inhibitor squeeze treatments
… must be re-squeezed before the scale inhibitor concentration in the produced water falls below the minimum inhibition concentration (MIC) required to prevent scaling. This work focuses on the pre-flush stage of a squeeze treatment, in which mutual solvents are applied in order to prepare the …
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Cellular Mechanism of Arglabin-Dimethylaminohydrochloride Cytotoxicity
… assay using expressed FTase showed that the 50% inhibition concentration of arglabin-DMA was 2.9 mM. The FTase assay using lysates of Ras/3T3 cells that had been incubated with arglabin-DMA showed that the highest FTase inhibition was 59% as compared to the no treatment control, and this …
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Anti-cancer Functions and Mechanisms of a pRb2/p130 Peptide Fragment
… E/A complexes. In vitro kinase assays showed the inhibition occurred in a dose-dependent manner. The half maximal inhibition concentration of the Spa310 in the kinase assay was 1.67mM. In addition, it has been shown that Spa310 peptide is able to inhibit the kinase activities of both Cdk2/Cyclin E …
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Biochemical characteristics and antimicrobial potential of seed and nut oils against Staphylococcus aureus
… oil showed better activity with clear zones of inhibitions. A combinational study of oils with conventional antibiotics shows that MRSA 252 and ATCC 6538 exhibited different reactions such as synergy, resistant, potentiation and indifference effects when combined with the oils. Minimum …
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An RNA-interference-based platform for genome analysis and engineering in Saccharomyces cerevisiae
… cerevisiae. After three rounds, the 100% growth inhibition concentration of HAc was elevated from 0.7% to 0.9% (v/v). The best engineered strain exhibited a significantly improved fermentation performance than the wild type strain under HAc stress. By combining the powerful toolboxes of RNAi and …
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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
… & M4b did not exhibit a MIC99 even at very high concentrations. Generally, an improvement in activity was observed where CPZ or its metabolites were used in combination with known anti-TB drugs. The combinations that exhibited a fractional inhibition concentration index (FICI) of < 0.5 were …
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Analysis of Zero-Heavy Data Using a Mixture Model Approach
… zeroes due to mortality. A joint estimate of inhibition concentration (ICx) is also developed as potency estimation based on the mixture model approach. It is found that the ZIP model would perform better than the regular Poisson model if the mortality is high. This kind of toxicity testing …
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Sequestration of metal and metalloid ions by thermophilic bacteria
… geothermally active habitat with relatively high concentrations of metalloid ions and compounds. In initial cadmium ion toxicity assays, the minimal inhibition concentration for 46 thermophilic bacteria of the genera Aneurinibacillus, Anoxybacillus, Bacillus, Brevibacillus, Geobacillus, and …
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Evaluation of Novel Carbamate Insecticides for Neurotoxicity to Non-Target Species
… the ultimate goal of malaria control. First, 50% inhibition concentration (IC50) data was collected from three mammalian AChEs with eight commercial carbamate insecticides by using the Ellman assay. The IC50 values varied from 57 nM to 7358 nM. The AChE sensitivity pattern and level were shown to …
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Antimicrobial, cytotoxic and prelimenary phytochemical analysis of four medicinal plants and their formulation
… the Broth dilution method. Minimum bactericidal concentration (MBC) of the extracts was determined by culturing the contents of minimum inhibitory concentration (MIC) on nutrient agar. Similarly, minimum fungicidal concentration (MFC) was also determined by culturing contents of MIC in sabouraud …
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Synthesis, Fractionation, Characterisation and Toxicity of Naphthenic Acids from Complex Mixtures
… results revealed that the toxicity endpoint (50% Inhibition Concentration, IC50) was between 0.004 and 0.7 mM. Exponential and other correlations were noted between carbon number and toxicity in several of the structural groups of acids assayed, which may be beneficial for predictions of toxicity …
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Synthesis, Characterization and Evaluation of Novel Treatment against Resistant Pathogenic Bacteria
… agar diffusion assay and the minimum inhibitory concentrations (MIC) were determined using the microdilution method. The minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were determined by sub-culturing from the MIC plates on Mueller-Hinton Agar. RESULTS: …