Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 57 for “"Inflammatory bowel diseases"”.
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The mucosal microbiome of inflammatory bowel diseases
… elucidate the mucosal associated microbiome in Inflammatory Bowel Disease and finally examines the viability of using mucosal samples for shotgun metagenomics or metatranscriptomics. Taxonomic classification is a corner stone for the characterisation of microbial communities, but currently many …
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Metabolomic modelling and applications in inflammatory bowel diseases
… ulcerative colitis (UC) are major components of Inflammatory Bowel Disease (IBD), a multifactorial disorder most likely resulting from altered immune response to commensal or pathogenic gut microbes under the influence of environmental factors, such as diet. Exclusive Enteral Nutrition (EEN) is …
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Optimizing immunomodulator and anti-TNF treatment in Inflammatory Bowel Diseases.
Contains fulltext : 297656.pdf (Publisher’s version ) (Open Access)
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Investigating a Mitochondrial Fission Inhibitor as a Therapeutic for Inflammatory Bowel Diseases
… for its possible role in the pathogenesis of inflammatory bowel disease (IBD). The current study utilized the P110 peptide drug, a selective inhibitor of mitochondrial fission, to investigate the relationship between mitochondrial dynamics and colitis. First, the functionality of the P110 …
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Investigation of the TNF superfamily of ligands as potential therapeutic targets in inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are chronic diseases of the gut affecting a significant proportion of the population in the western world with increasing incidence globally. They are multifactorial diseases with susceptibility mediated by a combination of host genetics and environmental factors …
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Mass spectrometry-based protein profiling strategies for biomarker discovery in liver and inflammatory bowel diseases
… have been developed and applied to liver and inflammatory bowel diseases (IBDs) for the discovery of new biomarkers. The first of them, based on bulk solid-phase extraction combined with matrix-assisted laser desorption/ionization - Time of Flight mass spectrometry (MALDI-TOF MS) and …
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Role of cytokine IL-15 in the homeostasis of the intestinal epithelium and inflammatory bowel diseases
Inflammatory bowel diseases (IBD), such as Ulcerative Colitis and Crohn’s disease, are characterized by increased intestinal permeability caused by intestinal mucosal barrier dysfunction, a critical factor in the pathogenesis of IBD. The immune system is the major effector of this tissue damage, …
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The Impact of Study Methodology on Studying Genetic and Environmental Risk Factors for the Inflammatory Bowel Diseases
Inflammatory bowel disease (IBD), comprised of Crohn’s disease and ulcerative colitis, results from a complex interaction between genetic and environmental factors. NOD2 and cigarette smoking are two of the most commonly replicated genetic and environmental risk factors, respectively, for Crohn’s …
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Σύγχρονες βιολογικές θεραπείες για τα Ιδιοπαθή Φλεγμονώδη Νοσήματα του Εντέρου / Modern biological therapies for Inflammatory Bowel Diseases
… – κλειδιά που αξιοποιήθηκαν ήταν οι ακόλουθες: “Inflammatory Bowel Diseases”, IBD, “Ulcerative Colitis”, “Crohn’s disease”, “therapy” και “treatment”, ενώ για την επιλογή των καταλληλότερων άρθρων, ορίστηκαν συγκεκριμένα κριτήρια εισαγωγής και αποκλεισμού. Αποτελέσματα: Συνολικά, από την …
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Combining population-scale single-cell transcriptomics with germline genetics to understand the biology of inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are chronic, incurable diseases of the gastrointestinal tract with a high prevalence in the United Kingdom and a growing incidence worldwide. The two most common forms of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). Genome-wide association studies …
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Some Contemporary Diagnostic Aspects of Inflammatory Bowel Diseases in Children and Adolescents // Някои съвременни диагностични аспекти на възпалителните заболявания на червата при деца и юноши
При общо 76 деца, 36 с улцерозен колит, 27 с болест на Крои и 13 е неспецифичен колит, на средна възраст от 13,54±3,13 г. (между две и 17 г.), хоспитализирани между 1.1.2008 г. и 31.VII.2020 г., са проведени образни изследвания и са изследвани някои клинични характеристики на тези три заболявания, …
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Identification of bacteria-regulated mechanisms for the pathogenesis of inflammatory bowel diseases (IBD) and development of upconverting nanoparticle (UCNP) luminescence imaging for the monitoring of gut bacteria
Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract, including two inflammatory conditions Crohn’s disease (CD) and ulcerative colitis (UC). The environment, the gut microbiota, the genetic make-up and the immune response are believed to contribute to the …
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RELATIONSHIPS BETWEEN DIETARY FIBER STRUCTURAL FEATURES AND GROWTH AND UTILIZATION PATTERNS OF HUMAN GUT BACTERIA
… is associated with many diet-related chronic diseases such as obesity, diabetes, and inflammatory bowel diseases. In order to make a better choice of dietary fiber for a desired microbiota shift related to a health outcome, knowledge of fiber degradation and utilization by gut bacteria is …
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Signatures of gut microbes in human diseases
… as contributing factors in a wide range of human diseases. This work investigates how bacteria residing in the human large intestine – home to the densest microbial community in the body – contribute to the pathogenesis of three distinct conditions: Parkinson’s disease (PD), inflammatory bowel …
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The role of the inositol phosphatase, SHIP, in the innate immune response to Salmonella Typhimurium
… mice may be used to study the development of inflammatory bowel diseases characterized by fibrosis, such as Crohn's. Because SHIP is such a critical negative regulator in both innate and adaptive immune cells, it has the potential to significantly alter the outcome of infections. This work …
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The Impact of Maternal Methyl-Donor Nutrient Supplementation on Vitamin D Status and Inflammation among Adult Offspring
… development of secondary complications, such as inflammatory bowel diseases, cardiovascular diseases, and cancers. In addition to its classical role in bone health, the immunomodulatory role of VD has been widely reported. In this study, we aim to investigate the effect of maternal methyl-donor …
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Complex Evaluation of the Effectiveness of Biological Therapy in Patients with Active Ulcerative Colitis // Комплексна оценка на ефективността от биологична терапия при болни с активен язвен колит
Inflammatory bowel diseases (IBD), namely ulcerative colitis (UC) and Crohn's disease (CD), are chronic immune-mediated conditions with a high incidence in developed countries and a rapidly increasing incidence in highly industrialized countries. The pathogenesis of UC is complex and still unclear. …
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SYNDROMIC HIDRADENITIS SUPPURATIVA: GENOTYPE-PHENOTYPE CORRELATION THROUGH WHOLE-EXOME SEQUENCING IN 10 UNRELATED PATIENTS
… associated with systemic comorbidities such as inflammatory bowel diseases and arthritis, has not been completely elucidated. Objective: To describe clinical features and genetic signature of patients with the main syndromic HS forms, i.e., PASH, PAPASH, and PASH/SAPHO overlapping. Methods: …
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A Geographical Exploration of Inflammatory Bowel Disease
… that afflicts 200 000 Canadians of all ages, inflammatory bowel disease has no known cure or aetiology. Using socioeconomic Census variables, population-level models of inflammatory bowel diseases – Crohn's disease and ulcerative colitis – were made for two large cities in Alberta as well as …
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